Metabolic correlates of tumour hypoxia in malignant canine mammary carcinoma

Given its importance in human and canine tumour biology, a profound understanding of tumour hypoxia is of paramount importance. Therefore, the aim of this work was to investigate the relationship between tumour hypoxia and the expression of a number of hypoxia-induced proteins that play a role in tu...

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Veröffentlicht in:	Research in veterinary science 2011-12, Vol.91 (3), p.e125-e128
Hauptverfasser:	Mees, G., Vangestel, C., Dierckx, R., Loomans, S., Van Damme, N., Peremans, K., De Rooster, H., Van Goethem, B., Pauwels, P., Ducatelle, R., Van de Wiele, C.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Cancer carcinoma Dog Diseases - metabolism Dog Diseases - surgery Dogs Female Gene Expression Regulation, Neoplastic - physiology Glucose Glucose Transporter Type 1 - genetics Glucose Transporter Type 1 - metabolism GLUT humans Hypoxia Immunohistochemistry Mammary Neoplasms, Animal - metabolism Mammary Neoplasms, Animal - surgery Nitroimidazoles Oxygen Consumption Pimonidazole protein metabolism proteins Radiation-Sensitizing Agents Staining and Labeling Studies Tumour hypoxia Veterinary medicine
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