Endothelial nitric oxide synthase gene haplotype association with systemic lupus erythematosus

Endothelial nitric oxide synthase (eNOS) catalyses the production of nitric oxide, which has been shown to participate in the pathogenesis of systemic lupus erythematosus (SLE). eNOS gene polymorphism may have an effect on eNOS gene expression, eNOS protein synthesis and enzymatic activity. We inves...

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Veröffentlicht in:	Lupus 2011-06, Vol.20 (7), p.700-708
Hauptverfasser:	AlFadhli, S, AlTamimy, B, AlSaeid, K, Haider, MZ
Format:	Artikel
Sprache:	eng
Schlagworte:	Adolescent Adult Case-Control Studies Catalysis Enzymatic activity Enzymes Female Gene polymorphism Genetic Predisposition to Disease Genotype & phenotype Haplotypes Health sciences Humans Introns Linkage Disequilibrium Lupus Lupus Erythematosus, Systemic - enzymology Lupus Erythematosus, Systemic - genetics Male Medical laboratories Middle Aged Nitric oxide Nitric Oxide - metabolism Nitric Oxide Synthase Type III - genetics Nitric-oxide synthase Pathogenesis Polymerase chain reaction Polymorphism Polymorphism, Single Nucleotide Protein biosynthesis Proteins Rheumatology Single-nucleotide polymorphism Systemic lupus erythematosus Tandem Repeat Sequences Young Adult
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