Dimethyl sulfoxide (DMSO) attenuates the inflammatory response in the in vitro intestinal Caco-2 cell model

► DMSO at low concentrations (0.1–0.5%) modulated the intestinal inflammatory response in vitro. ► DMSO reduced IL-6 and MCP-1 secretions in inflamed Caco-2 cells. ► DMSO decreased prostaglandin-E2 production related to cyclooxygenase-2 activity. ► DMSO inhibited the gene transcription for several p...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Toxicology letters 2011-10, Vol.206 (3), p.268-275
Hauptverfasser:	Hollebeeck, Sylvie, Raas, Thomas, Piront, Neil, Schneider, Yves-Jacques, Toussaint, Olivier, Larondelle, Yvan, During, Alexandrine
Format:	Artikel
Sprache:	eng
Schlagworte:	Anti-Inflammatory Agents - pharmacology Antiinflammatory agents Biological and medical sciences Caco-2 Cells Chemokine CCL2 - secretion COX-2 activity Cytokines Dimethyl sulfoxide Dimethyl Sulfoxide - pharmacology Dinoprostone - biosynthesis Dose-Response Relationship, Drug Humans Interleukin-1beta - pharmacology Interleukin-6 - secretion Intestinal inflammation Medical sciences NF-kappa B - genetics RNA, Messenger - analysis Toxicology Transcriptional study
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!