Rhou maintains the epithelial architecture and facilitates differentiation of the foregut endoderm

Rhou encodes a Cdc42-related atypical Rho GTPase that influences actin organization in cultured cells. In mouse embryos at early-somite to early-organogenesis stages, Rhou is expressed in the columnar endoderm epithelium lining the lateral and ventral wall of the anterior intestinal portal. During f...

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Veröffentlicht in:	Development (Cambridge) 2011-10, Vol.138 (20), p.4511-4522
Hauptverfasser:	Loebel, David A F, Studdert, Joshua B, Power, Melinda, Radziewic, Tania, Jones, Vanessa, Coultas, Leigh, Jackson, Yvette, Rao, Renuka S, Steiner, Kirsten, Fossat, Nicolas, Robb, Lorraine, Tam, Patrick P L
Format:	Artikel
Sprache:	eng
Schlagworte:	Actins - metabolism Animals Base Sequence Cell Differentiation Cell Line Digestive System - embryology Digestive System - metabolism Embryonic Stem Cells - cytology Embryonic Stem Cells - metabolism Endoderm - cytology Endoderm - embryology Endoderm - metabolism Gene Expression Regulation, Developmental Gene Knockdown Techniques Hep G2 Cells Humans Intercellular Junctions - metabolism Intercellular Junctions - ultrastructure Mice Mice, Knockout NIH 3T3 Cells rho GTP-Binding Proteins - antagonists & inhibitors rho GTP-Binding Proteins - genetics rho GTP-Binding Proteins - metabolism RNA, Small Interfering - genetics Signal Transduction Wnt Proteins - metabolism
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