Toenail infection by Cladophialophora boppii

Cladophialophora boppii is a black yeast-like fungus that up to now has been only rarely described as a cause of human infection and whose role as a pathogen was not established despite its repeated isolation and genetic identification in these reports. Here we report the first case of a verified to...

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Veröffentlicht in:Medical mycology (Oxford) 2011-02, Vol.49 (2), p.190-193
Hauptverfasser: Brasch, J., Dressel, S., Müller-Wening, K., Hügel, R., von Bremen, D., de Hoog, G.S.
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container_end_page 193
container_issue 2
container_start_page 190
container_title Medical mycology (Oxford)
container_volume 49
creator Brasch, J.
Dressel, S.
Müller-Wening, K.
Hügel, R.
von Bremen, D.
de Hoog, G.S.
description Cladophialophora boppii is a black yeast-like fungus that up to now has been only rarely described as a cause of human infection and whose role as a pathogen was not established despite its repeated isolation and genetic identification in these reports. Here we report the first case of a verified toenail infection caused by this fungus in a woman without any systemic disease or evidence of immunodeficiency. Identical dark molds were isolated from the same toenail at three points of time. Species identification was performed by scrutinizing the isolates morphologic, physiologic and genetic characteristics which resulted in their identification as Cladophialophora boppii. Oral treatment with terbinafin plus topical ciclopiroxolamine was effective.
doi_str_mv 10.3109/13693786.2010.516458
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source MEDLINE; Oxford University Press Journals All Titles (1996-Current); EZB-FREE-00999 freely available EZB journals
subjects Aged
Ascomycota - classification
Ascomycota - genetics
Ascomycota - isolation & purification
Ascomycota - physiology
ciclopiroxolamine
Cladophialophora
Female
Humans
Immunodeficiency
Infection
Molds
Nails - microbiology
Nails - pathology
Onychomycosis - diagnosis
Onychomycosis - microbiology
Pathogens
Toenail
title Toenail infection by Cladophialophora boppii
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