Nestin expression in astrocytic tumors delineates tumor infiltration

Nestin is an intermediate filament protein expressed in undifferentiated cells during central nervous system development, and glioma is known to be a highly infiltrative tumor. We determined whether nestin was expressed in astrocytic tumors and could identify infiltrating tumor cells. We screened 65...

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Veröffentlicht in:	Brain tumor pathology 2010-04, Vol.27 (1), p.17-21
Hauptverfasser:	Kitai, Ryuhei, Horita, Ryosuke, Sato, Kazufumi, Yoshida, Kazuhiko, Arishima, Hidetaka, Higashino, Yoshifumi, Hashimoto, Norichika, Takeuchi, Hiroaki, Kubota, Toshihiko, Kikuta, Ken-Ichiro
Format:	Artikel
Sprache:	eng
Schlagworte:	Adolescent Adult Aged Aged, 80 and over Astrocytoma Astrocytoma - diagnosis Astrocytoma - metabolism Astrocytoma - pathology Biomarkers, Tumor - analysis Brain Neoplasms - diagnosis Brain Neoplasms - metabolism Brain Neoplasms - pathology Brain tumors Cancer Research Central nervous system Child Development Female Glioblastoma Glioblastoma - diagnosis Glioblastoma - metabolism Glioblastoma - pathology Glioma Humans Intermediate Filament Proteins - analysis Intermediate Filament Proteins - metabolism Intermediate Filament Proteins - physiology Intermediate filaments Male Medicine Medicine & Public Health Metastases Middle Aged Neoplasm Invasiveness Neoplasm Staging Nerve Tissue Proteins - analysis Nerve Tissue Proteins - metabolism Nerve Tissue Proteins - physiology Nestin Neurology Neurosurgery Oncology Original Article Pathology Substantia alba Tumor cells Young Adult
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