Visfatin induces neurite outgrowth in PC12 cells via ERK1/2 signaling pathway

▸ We investigated the neuritogenic effect of visfatin on PC12 cells. ▸ Visfatin expression was upregulated during cobalt chloride-induced neuritogenesis in PC12 cells. ▸ Visfatin induced neurite outgrowth in PC12 cells. ▸ Visfatin-induced outgrowth of neurites was mediated by ERK1/2 signaling pathwa...

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Veröffentlicht in:	Neuroscience letters 2011-10, Vol.504 (2), p.121-126
Hauptverfasser:	Kang, Young-Soon, Bae, Moon-Kyoung, Kim, Jee-Young, Jeong, Joo-Won, Yun, Il, Jang, Hye-Ock, Bae, Soo-Kyung
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Biological and medical sciences Blotting, Western Cell Survival - drug effects Cobalt - pharmacology CoCl2 Dose-Response Relationship, Drug Enzyme-Linked Immunosorbent Assay ERK1/2 Fundamental and applied biological sciences. Psychology Immunohistochemistry Indoles - pharmacology Mitogen-Activated Protein Kinase 1 - drug effects Mitogen-Activated Protein Kinase 1 - physiology Mitogen-Activated Protein Kinase 3 - drug effects Mitogen-Activated Protein Kinase 3 - physiology Neurite outgrowth Neurites - drug effects Nicotinamide Phosphoribosyltransferase - pharmacology PC12 Cells Rats Real-Time Polymerase Chain Reaction Serine Proteinase Inhibitors - pharmacology Sincalide - metabolism Vertebrates: nervous system and sense organs Visfatin
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