Metabolism-Induced Toxicity of Selegiline and Carbamazepine Studied with an In Vitro Method

Carbamazepine and selegiline, although neuroprotective themselves, are presumed to have toxic metabolites. The aim of this study was to investigate the possible metabolism-induced toxicity of selegiline and carbamazepine with a novel in vitro method: The drugs were incubated with target cells (neuro...

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Veröffentlicht in:The open toxicology journal 2008-09, Vol.2 (1), p.61-70
Hauptverfasser: Mannerstrom, Marika, Maenpaa, Hanna, Raty, Sari, Sand, Juhani, Ylikomi, Timo, Tahti, Hanna
Format: Artikel
Sprache:eng
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