Mutations in Fanconi anemia genes and the risk of esophageal cancer

The incidence of esophageal squamous cell carcinoma (ESCC) is very high in northeastern Iran. Previously, we reported a strong familial component of ESCC among Turkmens, who constitute approximately one-half of the population of this region. We hypothesized that the genes which cause Fanconi anemia...

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Veröffentlicht in:	Human genetics 2011-05, Vol.129 (5), p.573-582
Hauptverfasser:	Akbari, Mohammad R., Malekzadeh, Reza, Lepage, Pierre, Roquis, David, Sadjadi, Ali R., Aghcheli, Karim, Yazdanbod, Abbas, Shakeri, Ramin, Bashiri, Jafar, Sotoudeh, Masoud, Pourshams, Akram, Ghadirian, Parviz, Narod, Steven A.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aged Aged, 80 and over Anemia Anemias. Hemoglobinopathies Biological and medical sciences Biomedical and Life Sciences Biomedicine Cancer Carcinoma, Squamous Cell - genetics Classical genetics, quantitative genetics, hybrids Diseases of red blood cells DNA DNA repair Esophageal cancer Esophageal Neoplasms - genetics Esophagus Fanconi Anemia - genetics Fanconi Anemia Complementation Group D2 Protein - genetics Fanconi Anemia Complementation Group E Protein - genetics Fanconi Anemia Complementation Group L Protein - genetics Fanconi's anemia Female Fundamental and applied biological sciences. Psychology Gastroenterology. Liver. Pancreas. Abdomen Gene Function Genes Genes, BRCA2 Genetic aspects Genetic Predisposition to Disease Genetics of eukaryotes. Biological and molecular evolution Health aspects Hematologic and hematopoietic diseases Human Human Genetics Humans INDEL Mutation Iran - epidemiology Male Medical sciences Metabolic Diseases Middle Aged Molecular Medicine Mutation Original Investigation Proteins Risk Risk factors Squamous cell carcinoma Tumors
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