Quantitative analysis of lentiviral transgene expression in mice over seven generations

Lentiviral transgenesis is now recognized as an extremely efficient and cost-effective method to produce transgenic animals. Transgenes delivered by lentiviral vectors exhibited inheritable expression in many species including those which are refractory to genetic modification such as non-human prim...

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Veröffentlicht in:	Transgenic research 2010-10, Vol.19 (5), p.775-784
Hauptverfasser:	Wang, Yong, Song, Yong-tao, Liu, Qin, Liu, Cang'e, Wang, Lu-lu, Liu, Yu, Zhou, Xiao-yang, Wu, Jun, Wei, Hong
Format:	Artikel
Sprache:	eng
Schlagworte:	Animal Genetics and Genomics Animals Biological and medical sciences Biomedical and Life Sciences Biomedical Engineering/Biotechnology Biotechnology Bisulfite CpG Islands - genetics Crosses, Genetic Data processing Disease transmission DNA Methylation epigenetics Expression vectors Fatty acid-binding protein Female Fluorometry FQ-PCR Fundamental and applied biological sciences. Psychology Gene Expression Regulation Genetic Engineering Genetic technics Genetic Vectors - genetics Genetic Vectors - physiology Genomes Green Fluorescent Proteins - biosynthesis Green Fluorescent Proteins - genetics Intestine Lentiviral transgenesis Lentivirus - genetics Lentivirus - physiology Life Sciences Male Methods. Procedures. Technologies Methylation Mice Mice, Transgenic - genetics Molecular Medicine Original Paper Plant Genetics and Genomics Polymerase Chain Reaction Position effects Primates Promoter Regions, Genetic - genetics quantitative analysis Recombinant Fusion Proteins - biosynthesis Recombinant Fusion Proteins - genetics ribosomal protein S18 Sequence Analysis, DNA Specific Pathogen-Free Organisms Time Factors Transgenes Transgenic animals and transgenic plants Transgenic mice Transgenics Ubiquitin C - genetics Virus Integration
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