Characterisation of eGFP-transgenic BALB/c mouse strain established by lentiviral transgenesis

Lentiviral technology is a powerful tool for the creation of stable transgenic animals. However, uncertainties have remained whether constitutive promoters resist long-term silencing. We used concentrated HIV-1 based lentiviral vectors to create stable transgenic BALB/c mice by perivitelline injecti...

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Veröffentlicht in:	Transgenic research 2010-02, Vol.19 (1), p.105-112
Hauptverfasser:	Kvell, Krisztián, Czömpöly, Tamás, Hiripi, László, Balogh, Péter, Kóbor, József, Bodrogi, Lilla, Pongrácz, Judit E., Ritchie, William A., Bősze, Zsuzsanna
Format:	Artikel
Sprache:	eng
Schlagworte:	Animal Genetics and Genomics Animals Animals, Newborn Biological and medical sciences Biomedical and Life Sciences Biomedical Engineering/Biotechnology Biotechnology Bone marrow Brief Communication Chimeras Efficiency Expression vectors Female Fluorescence Fundamental and applied biological sciences. Psychology Gene expression Gene Silencing - physiology Gene Transfer Techniques Genetic Engineering Genetic technics Green Fluorescent Proteins - genetics Human immunodeficiency virus 1 imaging Inheritance Patterns Lentivirus - genetics Life Sciences Male Methods. Procedures. Technologies Mice Mice, Inbred BALB C Mice, Transgenic - genetics Molecular Medicine Mosaicism Neonates Plant Genetics and Genomics Polymerase chain reaction Promoters Recombinant Fusion Proteins - genetics Transgenic animals Transgenic animals and transgenic plants Transgenics
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