Upregulation of Peroxiredeoxin III in the Hippocampus of Acute Immobilization Stress Model Rats and the Foxo3a-Dependent Expression in PC12 Cells

Stress induces structural plasticity in neurons of the adult central nervous system (CNS) and alters the levels of cellular production of reactive oxygen species (ROS), and these changes might involve modifications of the antioxidant defense system. This study investigated whether acute stress alter...

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Veröffentlicht in:	Cellular and molecular neurobiology 2011-10, Vol.31 (7), p.1041-1046
Hauptverfasser:	Jeong, Hee Jeong, Jeong, Hee Won, Song, Su Sung, Kang, Joon Won, Seo, Je Hoon, Lee, Young Ho, Lee, Keon Su, Kim, Dong Woon
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Biomedical and Life Sciences Biomedicine Cell Biology Forkhead Box Protein O3 Forkhead Transcription Factors - genetics Forkhead Transcription Factors - metabolism Hippocampus - cytology Hippocampus - enzymology Humans Immobilization - physiology Immobilization - psychology Male Mitochondria - enzymology Neurobiology Neurosciences Original Research PC12 Cells Peroxiredoxin III - genetics Peroxiredoxin III - metabolism Rats Rats, Sprague-Dawley RNA, Small Interfering - genetics RNA, Small Interfering - metabolism Spinal Cord - cytology Spinal Cord - enzymology Stress, Psychological - metabolism Superoxide Dismutase - metabolism Up-Regulation
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