Nuclear overexpression of lymphoid-enhancer-binding factor 1 identifies chronic lymphocytic leukemia small lymphocytic lymphoma in small B-cell lymphomas

Lymphoid-enhancer-binding factor 1 (LEF1), coupling with β -catenin, functions as a key nuclear mediator of WNT/ β -catenin signaling, which regulates cell proliferation and survival. LEF1 has an important role in lymphopoiesis, and is normally expressed in T and pro-B cells but not mature B cells....

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