Impaired B cell development in the absence of Krüppel-like factor 3

Krüppel-like factor 3 (Klf3) is a member of the Klf family of transcription factors. Klfs are widely expressed and have diverse roles in development and differentiation. In this study, we examine the function of Klf3 in B cell development by studying B lymphopoiesis in a Klf3 knockout mouse model. W...

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Veröffentlicht in:	The Journal of immunology (1950) 2011-11, Vol.187 (10), p.5032-5042
Hauptverfasser:	Vu, Thi Thanh, Gatto, Dominique, Turner, Vivian, Funnell, Alister P W, Mak, Ka Sin, Norton, Laura J, Kaplan, Warren, Cowley, Mark J, Agenès, Fabien, Kirberg, Jörg, Brink, Robert, Pearson, Richard C M, Crossley, Merlin
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals B-Lymphocyte Subsets - immunology B-Lymphocyte Subsets - metabolism B-Lymphocyte Subsets - pathology Bone Marrow Cells - immunology Bone Marrow Cells - metabolism Bone Marrow Cells - pathology Cell Differentiation - genetics Cell Differentiation - immunology Kruppel-Like Transcription Factors - deficiency Kruppel-Like Transcription Factors - genetics Lymphopoiesis - genetics Lymphopoiesis - immunology Mice Mice, Inbred C57BL Mice, Knockout Peritoneum - immunology Peritoneum - metabolism Peritoneum - pathology Radiation Chimera - genetics Radiation Chimera - immunology Spleen - immunology Spleen - metabolism Spleen - pathology
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