Targeted annotation of immunoglobulin light chain (IgL) genes in zebrafish from BAC clones reveals kappa-like recombining/deleting elements within IgL constant regions

Genomic organization, composition, and microsynteny of immunoglobulin light chain (IgL) gene segments in the zebrafish were analyzed through the identification and annotation of overlapping BAC clone insert sequences and an Illumina de novo assembly. The resultant gap-free IgL annotation confirmed a...

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Veröffentlicht in:	Fish & shellfish immunology 2011-11, Vol.31 (5), p.697-703
Hauptverfasser:	Zimmerman, Anastasia M., Romanowski, Krzysztof E., Maddox, Benjamin J.
Format:	Artikel
Sprache:	eng
Schlagworte:	Amino Acid Sequence Animals B cells Base Sequence Chromosomes, Artificial, Bacterial - genetics Clone Cells Danio rerio Fish Freshwater Gene Order Genes, Immunoglobulin Light Chain - genetics Immunoglobulin Constant Regions - chemistry Immunoglobulin Constant Regions - genetics Immunology Molecular Sequence Annotation Molecular Sequence Data Sequence Alignment Teleostei Zebrafish - genetics
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