Domino liver transplantation for familial amyloid polyneuropathy
Familial amyloid polyneuropathy is an autosomal dominant disorder in which the liver produces a variant prealbumin that is deposited along nerves, leading to a progressive and fatal polyneuropathy that begins in the third decade of life. Liver transplantation has been the only successful treatment t...
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| Veröffentlicht in: | Liver Transplantation and Surgery 1998-05, Vol.4 (3), p.236-238 |
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| container_title | Liver Transplantation and Surgery |
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| creator | Hemming, Alan W. Cattral, Mark S. Chari, Ravi S. Greig, Paul D. Lilly, Leslie B. Ashby, Peter Levy, Gary A. |
| description | Familial amyloid polyneuropathy is an autosomal dominant disorder in which the liver produces a variant prealbumin that is deposited along nerves, leading to a progressive and fatal polyneuropathy that begins in the third decade of life. Liver transplantation has been the only successful treatment to date. Apart from the production of the variant protein, there are no other abnormalities in these amyloid livers. We describe two cases in which, at the time of transplantation, the amyloid livers were subsequently used for transplantation in another patient, and we discuss the implications. |
| doi_str_mv | 10.1002/lt.500040303 |
| format | Article |
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Liver transplantation has been the only successful treatment to date. Apart from the production of the variant protein, there are no other abnormalities in these amyloid livers. We describe two cases in which, at the time of transplantation, the amyloid livers were subsequently used for transplantation in another patient, and we discuss the implications.</description><identifier>ISSN: 1074-3022</identifier><identifier>ISSN: 1527-6465</identifier><identifier>EISSN: 1527-6473</identifier><identifier>DOI: 10.1002/lt.500040303</identifier><identifier>PMID: 9563964</identifier><language>eng</language><publisher>Philadelphia, PA: W.B. 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Liver transplantation has been the only successful treatment to date. Apart from the production of the variant protein, there are no other abnormalities in these amyloid livers. We describe two cases in which, at the time of transplantation, the amyloid livers were subsequently used for transplantation in another patient, and we discuss the implications.</description><subject>Adult</subject><subject>Amyloid Neuropathies - genetics</subject><subject>Amyloid Neuropathies - surgery</subject><subject>Disease Transmission, Infectious</subject><subject>Humans</subject><subject>Liver Transplantation - methods</subject><subject>Male</subject><issn>1074-3022</issn><issn>1527-6465</issn><issn>1527-6473</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1998</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp9kE1LxDAURYMoo47u3Apd6caOL0nTJjtl_IQBN-M6pG2CkbSpSav031uZYdzN6l24h8PjInSBYYEByK3rFwwAMqBAD9AJZqRI86ygh1OGIkspEHKMTmP8nKgiy8UMzQTLqcizE3T34Bvb-sTZbx2SPqg2dk61veqtbxPjQ2JUY51VLlHN6Lytk867sdVD8J3qP8YzdGSUi_p8e-fo_elxvXxJV2_Pr8v7VVplOacpAVoxnitlBFeCkDojnDID3GBuCAdTKlYwghWvRckqneGqwqY0hKgaC43pHF1vvF3wX4OOvWxsrLSbntV-iFIAoVQAg4m82ksWgpOCMDKBNxuwCj7GoI3sgm1UGCUG-TetdL3cTTvhl1vvUDa63sHbLaeebfof6_S41yVX63_vLxMVg5s</recordid><startdate>199805</startdate><enddate>199805</enddate><creator>Hemming, Alan W.</creator><creator>Cattral, Mark S.</creator><creator>Chari, Ravi S.</creator><creator>Greig, Paul D.</creator><creator>Lilly, Leslie B.</creator><creator>Ashby, Peter</creator><creator>Levy, Gary A.</creator><general>W.B. 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Liver transplantation has been the only successful treatment to date. Apart from the production of the variant protein, there are no other abnormalities in these amyloid livers. We describe two cases in which, at the time of transplantation, the amyloid livers were subsequently used for transplantation in another patient, and we discuss the implications.</abstract><cop>Philadelphia, PA</cop><pub>W.B. Saunders</pub><pmid>9563964</pmid><doi>10.1002/lt.500040303</doi><tpages>3</tpages><oa>free_for_read</oa></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 1074-3022 |
| ispartof | Liver Transplantation and Surgery, 1998-05, Vol.4 (3), p.236-238 |
| issn | 1074-3022 1527-6465 1527-6473 |
| language | eng |
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| source | MEDLINE; Wiley Online Library Journals Frontfile Complete; Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals; Alma/SFX Local Collection |
| subjects | Adult Amyloid Neuropathies - genetics Amyloid Neuropathies - surgery Disease Transmission, Infectious Humans Liver Transplantation - methods Male |
| title | Domino liver transplantation for familial amyloid polyneuropathy |
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