Congenital tremor with spongy degeneration of the central nervous system in two puppies

Two crossbred puppies exhibited a generalized tremor that was accentuated by excitement or voluntary movement. Hypermetria was also present. Neurohistologic examination showed a bilaterally symmetric spongy condition, predominantly of the gray matter in the brain and spinal cord. These two dogs were...

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Veröffentlicht in:Journal of veterinary internal medicine 1991-03, Vol.5 (2), p.87-90
Hauptverfasser: Cachin, M. (University of Berne, Switzerland), Vandevelde, M
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creator Cachin, M. (University of Berne, Switzerland)
Vandevelde, M
description Two crossbred puppies exhibited a generalized tremor that was accentuated by excitement or voluntary movement. Hypermetria was also present. Neurohistologic examination showed a bilaterally symmetric spongy condition, predominantly of the gray matter in the brain and spinal cord. These two dogs were different, both in their clinical presentation and histologic appearance, from other reported cases of spongy degeneration. The clinicopathologic correlation between spongy degeneration and tremor is unclear. Spongy degeneration should be included in the differential diagnosis of tremor syndromes in puppies.
doi_str_mv 10.1111/j.1939-1676.1991.tb00937.x
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(University of Berne, Switzerland)</au><au>Vandevelde, M</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Congenital tremor with spongy degeneration of the central nervous system in two puppies</atitle><jtitle>Journal of veterinary internal medicine</jtitle><addtitle>J Vet Intern Med</addtitle><date>1991-03</date><risdate>1991</risdate><volume>5</volume><issue>2</issue><spage>87</spage><epage>90</epage><pages>87-90</pages><issn>0891-6640</issn><eissn>1939-1676</eissn><abstract>Two crossbred puppies exhibited a generalized tremor that was accentuated by excitement or voluntary movement. Hypermetria was also present. Neurohistologic examination showed a bilaterally symmetric spongy condition, predominantly of the gray matter in the brain and spinal cord. These two dogs were different, both in their clinical presentation and histologic appearance, from other reported cases of spongy degeneration. 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source Wiley Online Library Open Access
subjects Animals
BRAIN
BRAIN STEM
CACHORRO
CASE REPORTS
Central Nervous System - pathology
CEREBRAL CORTEX
CEREBRO
CHIOT
Diagnosis, Differential
Dog Diseases - congenital
Dog Diseases - pathology
Dogs
DYSREGULATION
ENCEPHALE
GENETIC DISORDERS
GRAY MATTER
HISTOPATHOLOGY
Male
MEDULA ESPINAL
MOELLE EPINIERE
PATHOLOGIE
PATHOLOGY
PATOLOGIA
PUPPIES
SPINAL CORD
TRASTORNOS DEL MECANISMO REGULADOR
TRASTORNOS GENETICOS
Tremor - congenital
Tremor - pathology
Tremor - veterinary
TROUBLE DE LA REGULATION
TROUBLE GENETIQUE
WHITE MATTER
title Congenital tremor with spongy degeneration of the central nervous system in two puppies
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