Nelfinavir, a protease inhibitor, increases sirolimus levels in a liver transplantation patient: A case report

With the increasing success of liver transplantation and the proven effectiveness of highly active retroviral therapy in HIV-positive patients, liver transplantation has been performed successfully in selected HIV-positive recipients with CD4 and an HIV viral load response to highly active antiretro...

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Veröffentlicht in:	Liver transplantation 2002-09, Vol.8 (9), p.838-840
Hauptverfasser:	Jain, Ashok Kumar B., Venkataramanan, Raman, Fridell, Jonathan A., Gadomski, Mary, Shaw, Leslie M., Ragni, Margaret, Korecka, Magdalena, Fung, John
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Cadavers Case reports CD4 antigen Disposition Female Graft rejection Graft Rejection - drug therapy highly active antiretroviral therapy HIV Infections - complications HIV Protease Inhibitors - therapeutic use Human immunodeficiency virus Humans Immunosuppressive agents Immunosuppressive Agents - blood Immunosuppressive Agents - therapeutic use Kinetics Liver diseases Liver Failure - complications Liver Failure - surgery Liver Transplantation Nelfinavir Nelfinavir - therapeutic use Nevirapine non-nucleoside reverse transcriptase inhibitors Osmolar Concentration Pharmacokinetics Proteinase inhibitors sirolimus Sirolimus - blood Sirolimus - therapeutic use Steroid hormones Tacrolimus
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