$Predictive value of the fraction of cancer cells immunolabeled for proliferating cell nuclear antigen or Ki67 in biopsies of head and neck carcinomas to identify lymph node metastasis: Comparison with clinical and radiologic examinations$

Predictive value of the fraction of cancer cells immunolabeled for proliferating cell nuclear antigen or Ki67 in biopsies of head and neck carcinomas to identify lymph node metastasis: Comparison with clinical and radiologic examinations

Background. Neck metastasis is a major prognostic factor of head and neck carcinoma, but its preoperative detection is currently unreliable. Molecular markers of the metastatic potential of a carcinoma would help to avoid unnecessary neck dissection in patients with nonmetastatic cancer. Methods. Th...

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Veröffentlicht in:	Head & neck 2003-04, Vol.25 (4), p.280-288
Hauptverfasser:	Liu, Ming, Lawson, Georges, Delos, Monique, Jamart, Jacques, Ide, Christophe, Coche, Emmanuel, Weynand, Birgit, Desuter, Gauthier, Hamoir, Marc, Remacle, Marc, Marbaix, Etienne
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aged Aged, 80 and over Biological and medical sciences Biopsy Carcinoma Carcinoma, Squamous Cell - diagnosis Carcinoma, Squamous Cell - immunology Carcinoma, Squamous Cell - secondary Cell Fractionation Female Head head and neck Head and neck cancer Host-tumor relations. Immunology. Biological markers Humans Immunohistochemistry Ki-67 Antigen - immunology Ki67 Laryngeal Neoplasms - diagnosis Laryngeal Neoplasms - immunology Laryngeal Neoplasms - pathology Lymph nodes Lymphatic Metastasis - diagnostic imaging Lymphatic Metastasis - immunology Lymphatic Metastasis - pathology Magnetic Resonance Imaging Male Medical sciences Metastases metastasis Middle Aged Mouth Neoplasms - diagnosis Mouth Neoplasms - immunology Mouth Neoplasms - pathology Neck Otorhinolaryngology (head neck, general aspects and miscellaneous) Otorhinolaryngology. Stomatology PCNA Pharyngeal Neoplasms - diagnosis Pharyngeal Neoplasms - immunology Pharyngeal Neoplasms - pathology Predictive Value of Tests Proliferating cell nuclear antigen Proliferating Cell Nuclear Antigen - immunology Reproducibility of Results Sensitivity and Specificity Tomography, Spiral Computed Tumors
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