Cisapride stimulates contraction of idiopathic megacolonic smooth muscle in cats

We have previously shown that cisapride, a substituted piperidinyl benzamide, stimulates contraction of healthy feline colonic smooth muscle. The purpose of the present investigation was to determine the effect of cisapride on feline idiopathic megacolonic smooth muscle function. Longitudinal smooth...

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Veröffentlicht in:	Journal of veterinary internal medicine 1997-11, Vol.11 (6), p.313-318
Hauptverfasser:	Hasler, A.H, Washabau, R.J
Format:	Artikel
Sprache:	eng
Schlagworte:	ACETILCOLINA ACETYLCHOLINE Acetylcholine - pharmacology Animals Atropine - pharmacology CALCIO CALCIUM Cat Diseases CATS CHAT CHLORURE DE POTASSIUM Cisapride CLORURO POTASICO Colectomy Colon - drug effects Colon - physiopathology DOSAGE EFFECTS DRUGS EFECTOS DE DOSIFICACION EFFET DOSE GASTROINTESTINAL AGENTS Gastrointestinal Agents - pharmacology GATO GENETIC DISORDERS In Vitro Techniques INTESTIN INTESTINES INTESTINOS Isometric Contraction - drug effects MEDICAMENT MEDICAMENT GASTROINTESTINAL MEDICAMENTOS MEDICAMENTOS GASTROINTESTINALES Megacolon - physiopathology Megacolon - surgery Megacolon - veterinary MUSCLE MUSCLE CONTRACTION Muscle, Smooth - drug effects Muscle, Smooth - physiopathology MUSCLES MUSCULOS PEPTIDE PEPTIDES PEPTIDOS Piperidines - pharmacology POTASSIUM CHLORIDE Potassium Chloride - pharmacology SUBSTANCE P Substance P - pharmacology Tetrodotoxin - pharmacology TRASTORNOS GENETICOS TROUBLE GENETIQUE
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