Matrix metalloproteinases in inflammatory bowel disease: Boon or a bane?

Matrix metalloproteinases (MMPs) are a family of Zn2+‐dependent extracellular matrix (ECM) degrading endopeptidases that share common functional domains, activation mechanisms, and collectively have the capacity to degrade all types of ECM proteins. In addition to playing a central role in ECM turno...

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Veröffentlicht in:Inflammatory bowel diseases 2007-01, Vol.13 (1), p.97-107
Hauptverfasser: Ravi, Anupama, Garg, Pallavi, Sitaraman, Shanthi V.
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Sprache:eng
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