The immunotherapy of prostate cancer

Advanced prostate cancer remains incurable with standard treatment options. Immunotherapy may be a realistic alternative given the growing evidence that the immune response can affect the growth of other solid tumours and the regulation of both specific and shared prostate cancer antigens. Early stu...

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Veröffentlicht in:Prostate cancer and prostatic diseases 2000-12, Vol.3 (4), p.303-307
Hauptverfasser: Dalgleish, A G, Perry, M J A, Eaton, J D, Hrouda, D, Todryk, S M, Kirby, R S
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container_title Prostate cancer and prostatic diseases
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creator Dalgleish, A G
Perry, M J A
Eaton, J D
Hrouda, D
Todryk, S M
Kirby, R S
description Advanced prostate cancer remains incurable with standard treatment options. Immunotherapy may be a realistic alternative given the growing evidence that the immune response can affect the growth of other solid tumours and the regulation of both specific and shared prostate cancer antigens. Early studies suggest that both non-specific and specific vaccines can effect relevant animal models and clinical trials based on these observations are now in progress. A number of other approaches including gene therapy with HSVtk are already undergoing clinical studies (Herman et al. Hum Gene Ther 1999; 10: 1239-1249). Prostate Cancer and Prostatic Diseases (2000) 3, 303-307
doi_str_mv 10.1038/sj.pcan.4500487
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source Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals; SpringerLink Journals - AutoHoldings
subjects Animal models
Antigens
Cancer vaccines
Clinical trials
Gene therapy
Immune response
Immune system
Immunotherapy
Prostate cancer
Solid tumors
Tumors
Vaccines
title The immunotherapy of prostate cancer
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