Analysis of a positional candidate gene for inflammatory bowel disease: NRAMP2

Genome scans have identified a region spanning 40 cM on the long arm of chromosome 12 as a susceptibility locus for inflammatory bowel disease (IBD). This locus contains several candidate genes for IBD, one of which is the gene for the natural resistance associated macrophage protein 2 (NRAMP2). Thi...

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Veröffentlicht in:	Inflammatory bowel diseases 2000-05, Vol.6 (2), p.92-98
Hauptverfasser:	Stokkers, Pieter C. F., Huibregtse, Kees, Leegwater, A. C., Reitsma, Pieter H., Tytgat, Guido N. J., Van Deventer, Sander J. H.
Format:	Artikel
Sprache:	eng
Schlagworte:	Cations Chromosome 12 Crohn's disease Exons Gene frequency Genetics Genomes Immunity Inflammatory bowel diseases Introns Linkage analysis Linkage disequilibrium Macrophages Mutation NRAMP2 Polymorphisms Population genetics Restriction fragment length polymorphism Risk factors Statistics Susceptibility Ulcerative colitis
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