Fecal calprotectin, lactoferrin, and endoscopic disease activity in monitoring anti‐TNF‐alpha therapy for Crohn's disease

Background: Fecal calprotectin and lactoferrin are promising noninvasive biomarkers for intestinal inflammation. In Crohn's disease (CD), during anti‐TNF‐alpha (TNF‐α) treatment, the clinical significance of these markers has, however, been insufficiently explored. Methods: Among CD patients re...

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Veröffentlicht in:	Inflammatory bowel diseases 2008-10, Vol.14 (10), p.1392-1398
Hauptverfasser:	Sipponen, Taina, Savilahti, Erkki, Kärkkäinen, Päivi, Kolho, Kaija‐Leena, Nuutinen, Hannu, Turunen, Ulla, Färkkilä, Martti
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Biomarkers - analysis Crohn Disease - diagnosis Crohn Disease - drug therapy Crohn Disease - pathology Crohn Disease - physiopathology Crohn's disease Crohn's disease index of severity Endoscopy, Gastrointestinal - methods fecal biomarkers Feces - chemistry Female Humans Lactoferrin - analysis Leukocyte L1 Antigen Complex - analysis Male mucosal healing Prognosis Sensitivity and Specificity Severity of Illness Index stool tests tumor necrosis factor α Tumor Necrosis Factor-alpha - antagonists & inhibitors Young Adult
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