Fluid flow induced calcium response in osteoblasts: Mathematical modeling

Abstract Fluid flow in the bone lacuno–canalicular network can induce dynamic fluctuation of intracellular calcium concentration ([Ca2+ ]i ) in osteoblasts, which plays an important role in bone remodeling. There has been limited progress in the mathematical modeling of this process probably due to...

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Veröffentlicht in:	Journal of biomechanics 2011-07, Vol.44 (11), p.2040-2046
Hauptverfasser:	Su, J.H, Xu, F, Lu, X.L, Lu, T.J
Format:	Artikel
Sprache:	eng
Schlagworte:	Adenosine triphosphatase Adenosine Triphosphate - metabolism ATP Biological and medical sciences Biomechanics. Biorheology Calcium Calcium - metabolism Calcium concentration Calcium Signaling Cells Cells, Cultured Fundamental and applied biological sciences. Psychology Gene expression Ion channel Ion Channels - metabolism Mathematical model Mathematical models Mechanotransduction, Cellular Models, Biological Nitric oxide Osteoblasts - metabolism Personal relationships Physical Medicine and Rehabilitation Purinergic receptor Receptors, Purinergic - metabolism Shear Strength Shear stress Studies Tissues, organs and organisms biophysics
Online-Zugang:	Volltext
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