Preparation and in vitro release behavior of urapidil hydrochloride loading into microspheres based on poly(L-lactide)

Microencapsulation of the antihypertensive drug urapidil hydrochloride was investigated as a means of controlling drug release and minimizing or eliminating local side effects. Poly(L-lactide) (PLLA) microspheres were prepared using an alternative oil-in-water (O/W) solvent-evaporation method such a...

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