Design and development of temperature sensitive porous poly(NIPAAm-AMPS) hydrogels for drug release of doxorubicin-a cancer chemotherapy drug

Temperature sensitive polymer network porous hydrogels were developed with N-Isopropylacrylamide (NIPAAm) and AMPS (2-acrylamido-2-methyl-1-propanesulfonicacid), as well as with sucrose as porogen by crosslinking with hydrophilic crosslinker N,N¹-methylenebisacrylamide (MBA). The temperature respons...

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Veröffentlicht in:	Journal of applied polymer science 2010-06, Vol.116 (6), p.3593-3602
Hauptverfasser:	Varaprasad, K, Ravindra, S, Reddy, N. Narayana, Vimala, K, Raju, K. Mohana
Format:	Artikel
Sprache:	eng
Schlagworte:	Applied sciences Biological and medical sciences Cancer Chemotherapy Crosslinking Differential scanning calorimetry doxorubicin lower critical solution temperature Drugs Exact sciences and technology General pharmacology Hydrogels Medical sciences Organic polymers Pharmaceutical technology. Pharmaceutical industry Pharmacology. Drug treatments Physicochemistry of polymers porous Properties and characterization Scanning electron microscopy Solution and gel properties Swelling swelling/deswelling kinetics
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