Formulation and release of doxycycline HCL from an ion activated in situ gelling delivery system for the treatment of periodontal disease

This study reports on the formulation of doxycycline HCL in an ion activated in situ gelling delivery system and its implications for the treatment of periodontal disease. The system is based on the use of alginate as the gelling agent and hydroxypropyl methylcellulose (HPMC) as a viscosity enhancin...

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Veröffentlicht in:	Journal of applied polymer science 2010-01, Vol.115 (2), p.811-816
Hauptverfasser:	Obaidat, Aiman A, Altamimi, Riham M, Hammad, Mohammad M
Format:	Artikel
Sprache:	eng
Schlagworte:	Activated Alginates Applied sciences Biological and medical sciences Delivery systems drug delivery systems Exact sciences and technology Formulations Gelation General pharmacology Medical sciences Organic polymers Periodontal disease Pharmaceutical technology. Pharmaceutical industry Pharmacology. Drug treatments Physicochemistry of polymers Properties and characterization Rheological properties Serums viscosity
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