In vitro controlled release of polymeric drug-saccharide conjugates with ketoprofen, ibuprofen, and naproxen pendants

Polymerizable monomers of glucose and three types of nonsteroidal anti‐inflammatory drugs were prepared. Free radical polymerization of the resulting monomers was carried out in DMF. The polymers with drug pendent were characterized using FTIR, NMR, and GPC spectroscopy. Following hydrolysis of poly...

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Veröffentlicht in:	Journal of applied polymer science 2011-08, Vol.121 (3), p.1654-1660
Hauptverfasser:	Wu, Chengyao, Xie, Jiangang, Branford-White, Christopher, Quan, Jing, Zhu, Limin
Format:	Artikel
Sprache:	eng
Schlagworte:	Applied sciences Biological and medical sciences controlled release copolymerization copolymers degradation Exact sciences and technology General pharmacology Materials science Medical sciences Organic polymers Pharmaceutical technology. Pharmaceutical industry Pharmacology. Drug treatments Physicochemistry of polymers Polymers Polymers with particular properties Preparation, kinetics, thermodynamics, mechanism and catalysts
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