17β-Estradiol administration attenuates seawater aspiration-induced acute lung injury in rats

Abstract There is very little evidence on the value of administering estrogen in cases of seawater drowning which can induce acute lung injury/acute respiratory distress syndrome (ALI/ARDS). Therefore, this study aimed to investigate whether 17β-estradiol (E2) treatment can attenuate seawater aspira...

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Veröffentlicht in:	Pulmonary pharmacology & therapeutics 2011-12, Vol.24 (6), p.673-681
Hauptverfasser:	Fan, Qixin, Zhao, Pengtao, Li, Jiahuan, Xie, Xiaoyan, Xu, Min, Zhang, Yong, Mu, Deguang, Li, Wangping, Sun, Ruilin, Liu, Wei, Nan, Yandong, Zhang, Bo, Jin, Faguang, Li, Zhichao
Format:	Artikel
Sprache:	eng
Schlagworte:	17β-Estradiol Acute lung injury Acute Lung Injury - drug therapy Acute Lung Injury - metabolism Acute Lung Injury - pathology Animals Aquaporin 1 - analysis Aquaporin 5 - analysis Aquaporins Carbon Dioxide - blood Estradiol - therapeutic use Estrogen Receptor beta - analysis Estrogen receptor β Extravascular Lung Water - drug effects Lung - pathology Male Medical Education Near Drowning - therapy Pulmonary/Respiratory Rats Rats, Sprague-Dawley Seawater - adverse effects Seawater aspiration
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