Spontaneous Formation of a Vesicle Multilayer on Top of an Exponentially Growing Polyelectrolyte Multilayer Mediated by Diffusing Poly-l-lysine
We observed the spontaneous formation of vesicle-multilayers on top of a polyelectrolyte multilayer (PEM). By varying the thickness of underlying PEM (uPEM) it was possible to tailor the amount of adsorbing liposomes. Thereby, the loading capacity could be increased up to 17 times with respect to a...
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| Veröffentlicht in: | The journal of physical chemistry. B 2011-11, Vol.115 (43), p.12386-12391 |
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| container_end_page | 12391 |
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| container_issue | 43 |
| container_start_page | 12386 |
| container_title | The journal of physical chemistry. B |
| container_volume | 115 |
| creator | Graf, Norma Thomasson, Elsa Tanno, Alexander Vörös, Janos Zambelli, Tomaso |
| description | We observed the spontaneous formation of vesicle-multilayers on top of a polyelectrolyte multilayer (PEM). By varying the thickness of underlying PEM (uPEM) it was possible to tailor the amount of adsorbing liposomes. Thereby, the loading capacity could be increased up to 17 times with respect to a monolayer of vesicles for an uPEM of 50.5 bilayers. We, furthermore, proved that the formation of the vesicle multilayer is due to the ability of poly-l-lysine to diffuse within the uPEM. This method could be interesting for applications in sensors and drug delivery systems where the increase in loading capacity is highly desired. |
| doi_str_mv | 10.1021/jp206700r |
| format | Article |
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| ispartof | The journal of physical chemistry. B, 2011-11, Vol.115 (43), p.12386-12391 |
| issn | 1520-6106 1520-5207 |
| language | eng |
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| source | MEDLINE; American Chemical Society Journals |
| subjects | B: Macromolecules, Soft Matter Bearing strength Diffusion Electrolytes - chemistry Formations Liposomes - chemistry Microscopy, Atomic Force Multilayers Physical chemistry Polyelectrolytes Polylysine - chemistry Quartz Crystal Microbalance Techniques Spontaneous Vesicles |
| title | Spontaneous Formation of a Vesicle Multilayer on Top of an Exponentially Growing Polyelectrolyte Multilayer Mediated by Diffusing Poly-l-lysine |
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