Bilateral pleurisy revealing a myelome with free light chains complicated with an osseous amylose
The osseous amyloidosis associated with a pleural effusion in a myeloma is a rare situation. We report a case of an association of these three disease entities for discussion. A 75-year-old man was admitted for chest pain and dyspnea with left sacred bone pain. The radiological assessment reported p...
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Veröffentlicht in: | Annales de biologie clinique (Paris) 2011-09, Vol.69 (5), p.593-596 |
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creator | El Boukhrissi, Fatima Balouch, Lhousaine Hachimi, Moulay Ahmed Hommadi, Abdelaziz Idrissi, My Mustapha Rguibi Bamou, Youssef |
description | The osseous amyloidosis associated with a pleural effusion in a myeloma is a rare situation. We report a case of an association of these three disease entities for discussion. A 75-year-old man was admitted for chest pain and dyspnea with left sacred bone pain. The radiological assessment reported pleurisy and bilateral lytic images of the sacrum with soft tissue invasion, the biochemical tests showed a lambda free light chain myeloma and bone biopsy reported amyloidosis. The occurrence of systemic amyloidosis in myeloma is well documented, but the osseous location is rare and rarely revealed. Pleural effusion is a known complication of myeloma but is exceptionally revealing; it is usually seen in the myeloma IgG and IgA but very rarely in free light chain myeloma. We reported here a case that represents an exceptional situation of complications of light chains myeloma to remember their possible occurrence and to insist for the clinician sensitizing to carry out investigations on time and avoid complications or at minimum to retard them. |
doi_str_mv | 10.1684/abc.2011.0621 |
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We reported here a case that represents an exceptional situation of complications of light chains myeloma to remember their possible occurrence and to insist for the clinician sensitizing to carry out investigations on time and avoid complications or at minimum to retard them.</description><identifier>ISSN: 0003-3898</identifier><identifier>DOI: 10.1684/abc.2011.0621</identifier><identifier>PMID: 22008141</identifier><language>fre</language><publisher>France</publisher><subject>Aged ; Amyloidosis - complications ; Amyloidosis - diagnosis ; Amyloidosis - etiology ; Amyloidosis - immunology ; Amyloidosis - pathology ; Bone Diseases, Metabolic - diagnosis ; Bone Diseases, Metabolic - etiology ; Bone Diseases, Metabolic - immunology ; Humans ; Immunoglobulin Light Chains - blood ; Immunoglobulin Light Chains - metabolism ; Male ; Multiple Myeloma - complications ; Multiple Myeloma - diagnosis ; Multiple Myeloma - immunology ; Pleurisy - complications ; Pleurisy - diagnosis ; Pleurisy - immunology ; Tomography, X-Ray Computed</subject><ispartof>Annales de biologie clinique (Paris), 2011-09, Vol.69 (5), p.593-596</ispartof><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,780,784,27924,27925</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/22008141$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>El Boukhrissi, Fatima</creatorcontrib><creatorcontrib>Balouch, Lhousaine</creatorcontrib><creatorcontrib>Hachimi, Moulay Ahmed</creatorcontrib><creatorcontrib>Hommadi, Abdelaziz</creatorcontrib><creatorcontrib>Idrissi, My Mustapha Rguibi</creatorcontrib><creatorcontrib>Bamou, Youssef</creatorcontrib><title>Bilateral pleurisy revealing a myelome with free light chains complicated with an osseous amylose</title><title>Annales de biologie clinique (Paris)</title><addtitle>Ann Biol Clin (Paris)</addtitle><description>The osseous amyloidosis associated with a pleural effusion in a myeloma is a rare situation. We report a case of an association of these three disease entities for discussion. A 75-year-old man was admitted for chest pain and dyspnea with left sacred bone pain. The radiological assessment reported pleurisy and bilateral lytic images of the sacrum with soft tissue invasion, the biochemical tests showed a lambda free light chain myeloma and bone biopsy reported amyloidosis. The occurrence of systemic amyloidosis in myeloma is well documented, but the osseous location is rare and rarely revealed. Pleural effusion is a known complication of myeloma but is exceptionally revealing; it is usually seen in the myeloma IgG and IgA but very rarely in free light chain myeloma. We reported here a case that represents an exceptional situation of complications of light chains myeloma to remember their possible occurrence and to insist for the clinician sensitizing to carry out investigations on time and avoid complications or at minimum to retard them.</description><subject>Aged</subject><subject>Amyloidosis - complications</subject><subject>Amyloidosis - diagnosis</subject><subject>Amyloidosis - etiology</subject><subject>Amyloidosis - immunology</subject><subject>Amyloidosis - pathology</subject><subject>Bone Diseases, Metabolic - diagnosis</subject><subject>Bone Diseases, Metabolic - etiology</subject><subject>Bone Diseases, Metabolic - immunology</subject><subject>Humans</subject><subject>Immunoglobulin Light Chains - blood</subject><subject>Immunoglobulin Light Chains - metabolism</subject><subject>Male</subject><subject>Multiple Myeloma - complications</subject><subject>Multiple Myeloma - diagnosis</subject><subject>Multiple Myeloma - immunology</subject><subject>Pleurisy - complications</subject><subject>Pleurisy - diagnosis</subject><subject>Pleurisy - immunology</subject><subject>Tomography, X-Ray Computed</subject><issn>0003-3898</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2011</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNo1kD1PwzAURT2AaCmMrMgbU4q_kjgjVBSQKrF0j16cl9bIToKdgPLvCWqZ7nJ0dXQIueNszTOtHqEya8E4X7NM8AuyZIzJROpCL8h1jJ-McaGlvCILIRjTXPElgWfrYMAAjvYOx2DjRAN-IzjbHihQP6HrPNIfOxxpExCps4fjQM0RbBup6XzvrJkf6hMCLe1ixG6MFPzkuog35LIBF_H2vCuy377sN2_J7uP1ffO0S_o05YlUtTJNI6DA2bJJldQmB4kNMlPUPM1EldZZU-SmMpXQaV7VQhhZiEoayAXKFXk43fah-xoxDqW30aBz0P7ZlAXjcw6l5Ezen8mx8liXfbAewlT-R5G_gdFjZA</recordid><startdate>201109</startdate><enddate>201109</enddate><creator>El Boukhrissi, Fatima</creator><creator>Balouch, Lhousaine</creator><creator>Hachimi, Moulay Ahmed</creator><creator>Hommadi, Abdelaziz</creator><creator>Idrissi, My Mustapha Rguibi</creator><creator>Bamou, Youssef</creator><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>7X8</scope></search><sort><creationdate>201109</creationdate><title>Bilateral pleurisy revealing a myelome with free light chains complicated with an osseous amylose</title><author>El Boukhrissi, Fatima ; 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We report a case of an association of these three disease entities for discussion. A 75-year-old man was admitted for chest pain and dyspnea with left sacred bone pain. The radiological assessment reported pleurisy and bilateral lytic images of the sacrum with soft tissue invasion, the biochemical tests showed a lambda free light chain myeloma and bone biopsy reported amyloidosis. The occurrence of systemic amyloidosis in myeloma is well documented, but the osseous location is rare and rarely revealed. Pleural effusion is a known complication of myeloma but is exceptionally revealing; it is usually seen in the myeloma IgG and IgA but very rarely in free light chain myeloma. We reported here a case that represents an exceptional situation of complications of light chains myeloma to remember their possible occurrence and to insist for the clinician sensitizing to carry out investigations on time and avoid complications or at minimum to retard them.</abstract><cop>France</cop><pmid>22008141</pmid><doi>10.1684/abc.2011.0621</doi><tpages>4</tpages></addata></record> |
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subjects | Aged Amyloidosis - complications Amyloidosis - diagnosis Amyloidosis - etiology Amyloidosis - immunology Amyloidosis - pathology Bone Diseases, Metabolic - diagnosis Bone Diseases, Metabolic - etiology Bone Diseases, Metabolic - immunology Humans Immunoglobulin Light Chains - blood Immunoglobulin Light Chains - metabolism Male Multiple Myeloma - complications Multiple Myeloma - diagnosis Multiple Myeloma - immunology Pleurisy - complications Pleurisy - diagnosis Pleurisy - immunology Tomography, X-Ray Computed |
title | Bilateral pleurisy revealing a myelome with free light chains complicated with an osseous amylose |
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