Bilateral pleurisy revealing a myelome with free light chains complicated with an osseous amylose

The osseous amyloidosis associated with a pleural effusion in a myeloma is a rare situation. We report a case of an association of these three disease entities for discussion. A 75-year-old man was admitted for chest pain and dyspnea with left sacred bone pain. The radiological assessment reported p...

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Veröffentlicht in:Annales de biologie clinique (Paris) 2011-09, Vol.69 (5), p.593-596
Hauptverfasser: El Boukhrissi, Fatima, Balouch, Lhousaine, Hachimi, Moulay Ahmed, Hommadi, Abdelaziz, Idrissi, My Mustapha Rguibi, Bamou, Youssef
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container_issue 5
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container_title Annales de biologie clinique (Paris)
container_volume 69
creator El Boukhrissi, Fatima
Balouch, Lhousaine
Hachimi, Moulay Ahmed
Hommadi, Abdelaziz
Idrissi, My Mustapha Rguibi
Bamou, Youssef
description The osseous amyloidosis associated with a pleural effusion in a myeloma is a rare situation. We report a case of an association of these three disease entities for discussion. A 75-year-old man was admitted for chest pain and dyspnea with left sacred bone pain. The radiological assessment reported pleurisy and bilateral lytic images of the sacrum with soft tissue invasion, the biochemical tests showed a lambda free light chain myeloma and bone biopsy reported amyloidosis. The occurrence of systemic amyloidosis in myeloma is well documented, but the osseous location is rare and rarely revealed. Pleural effusion is a known complication of myeloma but is exceptionally revealing; it is usually seen in the myeloma IgG and IgA but very rarely in free light chain myeloma. We reported here a case that represents an exceptional situation of complications of light chains myeloma to remember their possible occurrence and to insist for the clinician sensitizing to carry out investigations on time and avoid complications or at minimum to retard them.
doi_str_mv 10.1684/abc.2011.0621
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subjects Aged
Amyloidosis - complications
Amyloidosis - diagnosis
Amyloidosis - etiology
Amyloidosis - immunology
Amyloidosis - pathology
Bone Diseases, Metabolic - diagnosis
Bone Diseases, Metabolic - etiology
Bone Diseases, Metabolic - immunology
Humans
Immunoglobulin Light Chains - blood
Immunoglobulin Light Chains - metabolism
Male
Multiple Myeloma - complications
Multiple Myeloma - diagnosis
Multiple Myeloma - immunology
Pleurisy - complications
Pleurisy - diagnosis
Pleurisy - immunology
Tomography, X-Ray Computed
title Bilateral pleurisy revealing a myelome with free light chains complicated with an osseous amylose
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