Coronary heart disease and cerebrovascular disease mortality in young adults: recent trends in Europe

Background: Over the last two decades, mortality from coronary heart disease (CHD) and cerebrovascular disease (CVD) declined by about 30% in the European Union (EU). Design: We analyzed trends in CHD (X ICD codes: I20–I25) and CVD (X ICD codes: I60–I69) mortality in young adults (age 35–44 years) i...

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Veröffentlicht in:European journal of cardiovascular prevention and rehabilitation 2011-08, Vol.18 (4), p.627-634
Hauptverfasser: Bertuccio, Paola, Levi, Fabio, Lucchini, Francesca, Chatenoud, Liliane, Bosetti, Cristina, Negri, Eva, Vecchia, Carlo La
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container_issue 4
container_start_page 627
container_title European journal of cardiovascular prevention and rehabilitation
container_volume 18
creator Bertuccio, Paola
Levi, Fabio
Lucchini, Francesca
Chatenoud, Liliane
Bosetti, Cristina
Negri, Eva
Vecchia, Carlo La
description Background: Over the last two decades, mortality from coronary heart disease (CHD) and cerebrovascular disease (CVD) declined by about 30% in the European Union (EU). Design: We analyzed trends in CHD (X ICD codes: I20–I25) and CVD (X ICD codes: I60–I69) mortality in young adults (age 35–44 years) in the EU as a whole and in 12 selected European countries, over the period 1980–2007. Methods: Data were derived from the World Health Organization mortality database. With joinpoint regression analysis, we identified significant changes in trends and estimated average annual percent changes (AAPC). Results: CHD mortality rates at ages 35–44 years have decreased in both sexes since the 1980s for most countries, except for Russia (130/100,000 men and 24/100,000 women, in 2005–7). The lowest rates (around 9/100,000 men, 2/100,000 women) were in France, Italy and Sweden. In men, the steepest declines in mortality were in the Czech Republic (AAPC = −6.1%), the Netherlands (−5.2%), Poland (−4.5%), and England and Wales (−4.5%). Patterns were similar in women, though with appreciably lower rates. The AAPC in the EU was −3.3% for men (rate = 16.6/100,000 in 2005–7) and −2.1% for women (rate = 3.5/100,000). For CVD, Russian rates in 2005–7 were 40/100,000 men and 16/100,000 women, 5 to 10-fold higher than in most western European countries. The steepest declines were in the Czech Republic and Italy for men, in Sweden and the Czech Republic for women. The AAPC in the EU was −2.5% in both sexes, with steeper declines after the mid-late 1990s (rates = 6.4/100,000 men and 4.3/100,000 women in 2005–7). Conclusions: CHD and CVD mortality steadily declined in Europe, except in Russia, whose rates were 10 to 15-fold higher than those of France, Italy or Sweden. Hungary and Poland, and also Scotland, where CHD trends were less favourable than in other western European countries, also emerge as priorities for preventive interventions.
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Design: We analyzed trends in CHD (X ICD codes: I20–I25) and CVD (X ICD codes: I60–I69) mortality in young adults (age 35–44 years) in the EU as a whole and in 12 selected European countries, over the period 1980–2007. Methods: Data were derived from the World Health Organization mortality database. With joinpoint regression analysis, we identified significant changes in trends and estimated average annual percent changes (AAPC). Results: CHD mortality rates at ages 35–44 years have decreased in both sexes since the 1980s for most countries, except for Russia (130/100,000 men and 24/100,000 women, in 2005–7). The lowest rates (around 9/100,000 men, 2/100,000 women) were in France, Italy and Sweden. In men, the steepest declines in mortality were in the Czech Republic (AAPC = −6.1%), the Netherlands (−5.2%), Poland (−4.5%), and England and Wales (−4.5%). Patterns were similar in women, though with appreciably lower rates. The AAPC in the EU was −3.3% for men (rate = 16.6/100,000 in 2005–7) and −2.1% for women (rate = 3.5/100,000). For CVD, Russian rates in 2005–7 were 40/100,000 men and 16/100,000 women, 5 to 10-fold higher than in most western European countries. The steepest declines were in the Czech Republic and Italy for men, in Sweden and the Czech Republic for women. The AAPC in the EU was −2.5% in both sexes, with steeper declines after the mid-late 1990s (rates = 6.4/100,000 men and 4.3/100,000 women in 2005–7). Conclusions: CHD and CVD mortality steadily declined in Europe, except in Russia, whose rates were 10 to 15-fold higher than those of France, Italy or Sweden. Hungary and Poland, and also Scotland, where CHD trends were less favourable than in other western European countries, also emerge as priorities for preventive interventions.</description><identifier>ISSN: 1741-8267</identifier><identifier>EISSN: 1741-8275</identifier><identifier>DOI: 10.1177/1741826710389393</identifier><identifier>PMID: 21521726</identifier><language>eng</language><publisher>London, England: SAGE Publications</publisher><subject>Adult ; Age Distribution ; Age Factors ; Cerebrovascular Disorders - mortality ; Coronary Disease - mortality ; Europe - epidemiology ; Female ; Humans ; Linear Models ; Male ; Monte Carlo Method ; Mortality - trends ; Time Factors ; World Health Organization</subject><ispartof>European journal of cardiovascular prevention and rehabilitation, 2011-08, Vol.18 (4), p.627-634</ispartof><rights>The European Society of Cardiology 2011 Reprints and permissions: sagepub.co.uk/journalsPermissions.nav</rights><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c444t-ec3ce66138bf7d7d57e92f0b3f64682285c0ff1a5c2bd0e3a861eafde007f7f53</citedby><cites>FETCH-LOGICAL-c444t-ec3ce66138bf7d7d57e92f0b3f64682285c0ff1a5c2bd0e3a861eafde007f7f53</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://journals.sagepub.com/doi/pdf/10.1177/1741826710389393$$EPDF$$P50$$Gsage$$H</linktopdf><linktohtml>$$Uhttps://journals.sagepub.com/doi/10.1177/1741826710389393$$EHTML$$P50$$Gsage$$H</linktohtml><link.rule.ids>314,776,780,21799,27903,27904,43600,43601</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/21521726$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Bertuccio, Paola</creatorcontrib><creatorcontrib>Levi, Fabio</creatorcontrib><creatorcontrib>Lucchini, Francesca</creatorcontrib><creatorcontrib>Chatenoud, Liliane</creatorcontrib><creatorcontrib>Bosetti, Cristina</creatorcontrib><creatorcontrib>Negri, Eva</creatorcontrib><creatorcontrib>Vecchia, Carlo La</creatorcontrib><title>Coronary heart disease and cerebrovascular disease mortality in young adults: recent trends in Europe</title><title>European journal of cardiovascular prevention and rehabilitation</title><addtitle>Eur J Cardiovasc Prev Rehabil</addtitle><description>Background: Over the last two decades, mortality from coronary heart disease (CHD) and cerebrovascular disease (CVD) declined by about 30% in the European Union (EU). Design: We analyzed trends in CHD (X ICD codes: I20–I25) and CVD (X ICD codes: I60–I69) mortality in young adults (age 35–44 years) in the EU as a whole and in 12 selected European countries, over the period 1980–2007. Methods: Data were derived from the World Health Organization mortality database. With joinpoint regression analysis, we identified significant changes in trends and estimated average annual percent changes (AAPC). Results: CHD mortality rates at ages 35–44 years have decreased in both sexes since the 1980s for most countries, except for Russia (130/100,000 men and 24/100,000 women, in 2005–7). The lowest rates (around 9/100,000 men, 2/100,000 women) were in France, Italy and Sweden. In men, the steepest declines in mortality were in the Czech Republic (AAPC = −6.1%), the Netherlands (−5.2%), Poland (−4.5%), and England and Wales (−4.5%). Patterns were similar in women, though with appreciably lower rates. The AAPC in the EU was −3.3% for men (rate = 16.6/100,000 in 2005–7) and −2.1% for women (rate = 3.5/100,000). For CVD, Russian rates in 2005–7 were 40/100,000 men and 16/100,000 women, 5 to 10-fold higher than in most western European countries. The steepest declines were in the Czech Republic and Italy for men, in Sweden and the Czech Republic for women. The AAPC in the EU was −2.5% in both sexes, with steeper declines after the mid-late 1990s (rates = 6.4/100,000 men and 4.3/100,000 women in 2005–7). Conclusions: CHD and CVD mortality steadily declined in Europe, except in Russia, whose rates were 10 to 15-fold higher than those of France, Italy or Sweden. Hungary and Poland, and also Scotland, where CHD trends were less favourable than in other western European countries, also emerge as priorities for preventive interventions.</description><subject>Adult</subject><subject>Age Distribution</subject><subject>Age Factors</subject><subject>Cerebrovascular Disorders - mortality</subject><subject>Coronary Disease - mortality</subject><subject>Europe - epidemiology</subject><subject>Female</subject><subject>Humans</subject><subject>Linear Models</subject><subject>Male</subject><subject>Monte Carlo Method</subject><subject>Mortality - trends</subject><subject>Time Factors</subject><subject>World Health Organization</subject><issn>1741-8267</issn><issn>1741-8275</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2011</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp1kEtPwzAQhC0EoqVw54R84xTwI7ETbqgqD6kSFzhHjr0uqZK4-IHUf0-qlh6QOO1q55uRdhC6puSOUinvqcxpyYSkhJcVr_gJmu5OWclkcXrchZygixDWhLCcV9U5mjBaMCqZmCKYO-8G5bf4E5SP2LQBVACsBoM1eGi8-1ZBp075o9Y7H1XXxi1uB7x1aVhhZVIXwwP2oGGIOHoYTNjJi-TdBi7RmVVdgKvDnKGPp8X7_CVbvj2_zh-Xmc7zPGaguQYhKC8bK400hYSKWdJwK3JRMlYWmlhLVaFZYwhwVQoKyhogRFppCz5Dt_vcjXdfCUKs-zZo6Do1gEuhrkZQFpWQI0n2pPYuBA-23vi2H3uoKal33dZ_ux0tN4fw1PRgjobfMkcg2wNBraBeu-SH8dn_A38AZs2DDA</recordid><startdate>20110801</startdate><enddate>20110801</enddate><creator>Bertuccio, Paola</creator><creator>Levi, Fabio</creator><creator>Lucchini, Francesca</creator><creator>Chatenoud, Liliane</creator><creator>Bosetti, Cristina</creator><creator>Negri, Eva</creator><creator>Vecchia, Carlo La</creator><general>SAGE Publications</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>20110801</creationdate><title>Coronary heart disease and cerebrovascular disease mortality in young adults: recent trends in Europe</title><author>Bertuccio, Paola ; Levi, Fabio ; Lucchini, Francesca ; Chatenoud, Liliane ; Bosetti, Cristina ; Negri, Eva ; Vecchia, Carlo La</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c444t-ec3ce66138bf7d7d57e92f0b3f64682285c0ff1a5c2bd0e3a861eafde007f7f53</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2011</creationdate><topic>Adult</topic><topic>Age Distribution</topic><topic>Age Factors</topic><topic>Cerebrovascular Disorders - mortality</topic><topic>Coronary Disease - mortality</topic><topic>Europe - epidemiology</topic><topic>Female</topic><topic>Humans</topic><topic>Linear Models</topic><topic>Male</topic><topic>Monte Carlo Method</topic><topic>Mortality - trends</topic><topic>Time Factors</topic><topic>World Health Organization</topic><toplevel>online_resources</toplevel><creatorcontrib>Bertuccio, Paola</creatorcontrib><creatorcontrib>Levi, Fabio</creatorcontrib><creatorcontrib>Lucchini, Francesca</creatorcontrib><creatorcontrib>Chatenoud, Liliane</creatorcontrib><creatorcontrib>Bosetti, Cristina</creatorcontrib><creatorcontrib>Negri, Eva</creatorcontrib><creatorcontrib>Vecchia, Carlo La</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>European journal of cardiovascular prevention and rehabilitation</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Bertuccio, Paola</au><au>Levi, Fabio</au><au>Lucchini, Francesca</au><au>Chatenoud, Liliane</au><au>Bosetti, Cristina</au><au>Negri, Eva</au><au>Vecchia, Carlo La</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Coronary heart disease and cerebrovascular disease mortality in young adults: recent trends in Europe</atitle><jtitle>European journal of cardiovascular prevention and rehabilitation</jtitle><addtitle>Eur J Cardiovasc Prev Rehabil</addtitle><date>2011-08-01</date><risdate>2011</risdate><volume>18</volume><issue>4</issue><spage>627</spage><epage>634</epage><pages>627-634</pages><issn>1741-8267</issn><eissn>1741-8275</eissn><abstract>Background: Over the last two decades, mortality from coronary heart disease (CHD) and cerebrovascular disease (CVD) declined by about 30% in the European Union (EU). Design: We analyzed trends in CHD (X ICD codes: I20–I25) and CVD (X ICD codes: I60–I69) mortality in young adults (age 35–44 years) in the EU as a whole and in 12 selected European countries, over the period 1980–2007. Methods: Data were derived from the World Health Organization mortality database. With joinpoint regression analysis, we identified significant changes in trends and estimated average annual percent changes (AAPC). Results: CHD mortality rates at ages 35–44 years have decreased in both sexes since the 1980s for most countries, except for Russia (130/100,000 men and 24/100,000 women, in 2005–7). The lowest rates (around 9/100,000 men, 2/100,000 women) were in France, Italy and Sweden. In men, the steepest declines in mortality were in the Czech Republic (AAPC = −6.1%), the Netherlands (−5.2%), Poland (−4.5%), and England and Wales (−4.5%). Patterns were similar in women, though with appreciably lower rates. The AAPC in the EU was −3.3% for men (rate = 16.6/100,000 in 2005–7) and −2.1% for women (rate = 3.5/100,000). For CVD, Russian rates in 2005–7 were 40/100,000 men and 16/100,000 women, 5 to 10-fold higher than in most western European countries. The steepest declines were in the Czech Republic and Italy for men, in Sweden and the Czech Republic for women. The AAPC in the EU was −2.5% in both sexes, with steeper declines after the mid-late 1990s (rates = 6.4/100,000 men and 4.3/100,000 women in 2005–7). Conclusions: CHD and CVD mortality steadily declined in Europe, except in Russia, whose rates were 10 to 15-fold higher than those of France, Italy or Sweden. Hungary and Poland, and also Scotland, where CHD trends were less favourable than in other western European countries, also emerge as priorities for preventive interventions.</abstract><cop>London, England</cop><pub>SAGE Publications</pub><pmid>21521726</pmid><doi>10.1177/1741826710389393</doi><tpages>8</tpages><oa>free_for_read</oa></addata></record>
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subjects Adult
Age Distribution
Age Factors
Cerebrovascular Disorders - mortality
Coronary Disease - mortality
Europe - epidemiology
Female
Humans
Linear Models
Male
Monte Carlo Method
Mortality - trends
Time Factors
World Health Organization
title Coronary heart disease and cerebrovascular disease mortality in young adults: recent trends in Europe
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