White Matter Differences in Monozygotic Twins Discordant or Concordant for Obsessive-Compulsive Symptoms: A Combined Diffusion Tensor Imaging/Voxel-Based Morphometry Study

Background Neuroimaging studies of obsessive-compulsive disorder (OCD) patients point to deficits in cortico-striato-thalamo-cortical circuits that might include changes in white matter. The contribution of environmental and genetic factors to the various OCD-related changes in brain structures rema...

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Veröffentlicht in:	Biological psychiatry (1969) 2011-11, Vol.70 (10), p.969-977
Hauptverfasser:	den Braber, Anouk, van 't Ent, Dennis, Boomsma, Dorret I, Cath, Danielle C, Veltman, Dick J, Thompson, Paul M, de Geus, Eco J.C
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Brain - pathology Brain Mapping Cortico-striato-thalamo-cortical network diffusion tensor imaging Diffusion Tensor Imaging - methods Diseases in Twins - diagnosis Environment Female fractional anisotropy Humans Image Processing, Computer-Assisted Magnetic Resonance Imaging Male Middle Aged Nerve Fibers, Myelinated - pathology obsessive-compulsive behavior Obsessive-Compulsive Disorder - diagnosis Obsessive-Compulsive Disorder - genetics Psychiatry Risk Factors Surveys and Questionnaires Twins, Monozygotic voxel-based morphometry Young Adult
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