Comparison of the effects of N-acetyl cysteine and erdosteine in rats with renal injury caused by paracetamol intoxication

Aim: The aim of the present study was to investigate the therapeutic and preventive effects of N-acetyl cysteine and erdosteine on renal injury associated with paracetamol (acetaminophen) intoxication. Materials and methods: Female albino Wistar rats were divided into six groups: control; paracetamo...

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Veröffentlicht in:	Human & Experimental Toxicology 2011-09, Vol.30 (9), p.1350-1358
Hauptverfasser:	Kandiş, Hayati, Erkan, Melih Engin, Yildirim, Ümran, Güneş, Harun, Erbaş, Mesut, Yildirim, Hayriye AK, Gezer, Suat, Kara, İsmail Hamdi
Format:	Artikel
Sprache:	eng
Schlagworte:	Acetaminophen - toxicity Acetylcysteine - administration & dosage Acetylcysteine - therapeutic use Acute Kidney Injury - chemically induced Acute Kidney Injury - diagnostic imaging Acute Kidney Injury - metabolism Acute Kidney Injury - prevention & control Animals Antioxidants - administration & dosage Antioxidants - therapeutic use Biological and medical sciences Comparative studies Data Interpretation, Statistical Drug therapy Female Kidney - diagnostic imaging Kidney - pathology Kidney diseases Kidney Function Tests Medical sciences Radionuclide Imaging Rats Rats, Wistar Rodents Thioglycolates - administration & dosage Thioglycolates - therapeutic use Thiophenes - administration & dosage Thiophenes - therapeutic use Toxicology
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