Biomarker response in the earthworm Lumbricus terrestris exposed to chemical pollutants
Earthworms are important organisms for the soil ecosystem. They are sensitive to toxic chemicals and represent useful bioindicator organisms for soil biomonitoring. Recently the use of biomarkers in earthworms has been increasingly investigated for soil monitoring and assessment purpose. The aim of...
Gespeichert in:
| Veröffentlicht in: | The Science of the total environment 2011-09, Vol.409 (20), p.4456-4464 |
|---|---|
| Hauptverfasser: | , , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | 4464 |
|---|---|
| container_issue | 20 |
| container_start_page | 4456 |
| container_title | The Science of the total environment |
| container_volume | 409 |
| creator | Calisi, A. Lionetto, M.G. Schettino, T. |
| description | Earthworms are important organisms for the soil ecosystem. They are sensitive to toxic chemicals and represent useful bioindicator organisms for soil biomonitoring. Recently the use of biomarkers in earthworms has been increasingly investigated for soil monitoring and assessment purpose. The aim of the preset paper was to analyze the pollutant-induced response of a suite of cellular and biochemical biomarkers in the earthworm
Lumbricus terrestris exposed to copper sulphate or methiocarb in OECD soil at the maximal concentrations recommended in agriculture. These responses were compared to lifecycle parameters such as survival, growth and reproduction.
Granulocyte morphometric alteration, lysosomal membrane stability, metallothionein concentration, and acetylcholinesterase activity were considered. In either copper sulphate or methiocarb exposure conditions the mean percentage variation of the pollutant-induced molecular and cellular biomarkers was consistent with the whole organism end-point responses. In particular pollutant-induced granulocyte enlargement, detected in either copper sulphate or methiocarb exposed organisms, showed to be a potential general biomarker that may be directly linked to organism health. Compared to the other biological responses to pollutants, it showed high sensitivity to pollutant exposure suggesting its possible applications as a sensitive, simple, and quick general biomarker for monitoring and assessment applications.
► A suite of biomarkers was standardized in the earthworm L. terrestris for detecting the pollutant induced stress syndrome. ► Exposure to either copper sulphate or methiocarb induced dramatic granulocyte enlargement. ► Pollutant induced granulocyte enlargement showed high sensitivity to pollutant exposure compared to other biomarkers. ► Granulocyte enlargement showed to be a potential general biomarker suitable to be included in a multi-biomarker strategy. |
| doi_str_mv | 10.1016/j.scitotenv.2011.06.058 |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_899155933</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><els_id>S0048969711007145</els_id><sourcerecordid>1770328851</sourcerecordid><originalsourceid>FETCH-LOGICAL-c465t-1f042a3ca8a71159adc6a850585ec3cac1d5b15b44a21a33e58ab6fe17f014103</originalsourceid><addsrcrecordid>eNqFkM1u1DAURi0EotPCK4A3iG4SfJ04dpZtxU-lkbopYmk5zo3GQxIH2ynw9vVohrIDbyxZ5_r77iHkLbASGDQf9mW0LvmE80PJGUDJmpIJ9YxsQMm2AMab52TDWK2KtmnlGTmPcc_ykQpekjMOUlWcqw35du38ZMJ3DDRgXPwckbqZph1SNCHtfvow0e06dcHZNdKEIWMpuEjx1-Ij9jR5anc4OWtGuvhxXJOZU3xFXgxmjPj6dF-Qr58-3t98KbZ3n29vrraFrRuRChhYzU1ljTISQLSmt41RIq8i0OZnC73oQHR1bTiYqkKhTNcMCHJgUAOrLsj7479L8D_WXE1PLlocRzOjX6NWbQtCtFWVyct_kiAlq7hSAjIqj6gNPsaAg16Cy5Z-a2D64F_v9ZN_ffCvWaNz6Tz55hSydhP2T3N_hGfg3QkwMRsbgpmti3-5OsfXjGfu6shhlvfgMBwCcbbYu4A26d67_5Z5BFDXqXA</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>1770328851</pqid></control><display><type>article</type><title>Biomarker response in the earthworm Lumbricus terrestris exposed to chemical pollutants</title><source>MEDLINE</source><source>Access via ScienceDirect (Elsevier)</source><creator>Calisi, A. ; Lionetto, M.G. ; Schettino, T.</creator><creatorcontrib>Calisi, A. ; Lionetto, M.G. ; Schettino, T.</creatorcontrib><description>Earthworms are important organisms for the soil ecosystem. They are sensitive to toxic chemicals and represent useful bioindicator organisms for soil biomonitoring. Recently the use of biomarkers in earthworms has been increasingly investigated for soil monitoring and assessment purpose. The aim of the preset paper was to analyze the pollutant-induced response of a suite of cellular and biochemical biomarkers in the earthworm
Lumbricus terrestris exposed to copper sulphate or methiocarb in OECD soil at the maximal concentrations recommended in agriculture. These responses were compared to lifecycle parameters such as survival, growth and reproduction.
Granulocyte morphometric alteration, lysosomal membrane stability, metallothionein concentration, and acetylcholinesterase activity were considered. In either copper sulphate or methiocarb exposure conditions the mean percentage variation of the pollutant-induced molecular and cellular biomarkers was consistent with the whole organism end-point responses. In particular pollutant-induced granulocyte enlargement, detected in either copper sulphate or methiocarb exposed organisms, showed to be a potential general biomarker that may be directly linked to organism health. Compared to the other biological responses to pollutants, it showed high sensitivity to pollutant exposure suggesting its possible applications as a sensitive, simple, and quick general biomarker for monitoring and assessment applications.
► A suite of biomarkers was standardized in the earthworm L. terrestris for detecting the pollutant induced stress syndrome. ► Exposure to either copper sulphate or methiocarb induced dramatic granulocyte enlargement. ► Pollutant induced granulocyte enlargement showed high sensitivity to pollutant exposure compared to other biomarkers. ► Granulocyte enlargement showed to be a potential general biomarker suitable to be included in a multi-biomarker strategy.</description><identifier>ISSN: 0048-9697</identifier><identifier>EISSN: 1879-1026</identifier><identifier>DOI: 10.1016/j.scitotenv.2011.06.058</identifier><identifier>PMID: 21783228</identifier><identifier>CODEN: STENDL</identifier><language>eng</language><publisher>Kidlington: Elsevier B.V</publisher><subject>Acetylcholinesterase - metabolism ; Animal, plant and microbial ecology ; Animals ; Applied ecology ; Assessments ; Biological and medical sciences ; Biomarker ; Biomarkers - analysis ; Cellular ; Copper ; Copper sulfate ; Copper Sulfate - chemistry ; Copper Sulfate - toxicity ; Earthworm ; Ecotoxicology, biological effects of pollution ; Environmental Monitoring - methods ; Exposure ; Fundamental and applied biological sciences. Psychology ; General aspects ; Granulocytes - cytology ; Granulocytes - drug effects ; Hemolymph - drug effects ; Lumbricus terrestris ; Metallothionein - metabolism ; Methiocarb ; Methiocarb - chemistry ; Methiocarb - toxicity ; Monitoring ; Oligochaeta - drug effects ; Oligochaeta - growth & development ; Oligochaeta - metabolism ; Organisms ; Pollutant ; Pollutants ; Reproduction - drug effects ; Soil ; Soil (material) ; Soil Pollutants - chemistry ; Soil Pollutants - toxicity ; Techniques</subject><ispartof>The Science of the total environment, 2011-09, Vol.409 (20), p.4456-4464</ispartof><rights>2011 Elsevier B.V.</rights><rights>2015 INIST-CNRS</rights><rights>Copyright © 2011 Elsevier B.V. All rights reserved.</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c465t-1f042a3ca8a71159adc6a850585ec3cac1d5b15b44a21a33e58ab6fe17f014103</citedby><cites>FETCH-LOGICAL-c465t-1f042a3ca8a71159adc6a850585ec3cac1d5b15b44a21a33e58ab6fe17f014103</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://dx.doi.org/10.1016/j.scitotenv.2011.06.058$$EHTML$$P50$$Gelsevier$$H</linktohtml><link.rule.ids>314,780,784,3550,27924,27925,45995</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=24513402$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/21783228$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Calisi, A.</creatorcontrib><creatorcontrib>Lionetto, M.G.</creatorcontrib><creatorcontrib>Schettino, T.</creatorcontrib><title>Biomarker response in the earthworm Lumbricus terrestris exposed to chemical pollutants</title><title>The Science of the total environment</title><addtitle>Sci Total Environ</addtitle><description>Earthworms are important organisms for the soil ecosystem. They are sensitive to toxic chemicals and represent useful bioindicator organisms for soil biomonitoring. Recently the use of biomarkers in earthworms has been increasingly investigated for soil monitoring and assessment purpose. The aim of the preset paper was to analyze the pollutant-induced response of a suite of cellular and biochemical biomarkers in the earthworm
Lumbricus terrestris exposed to copper sulphate or methiocarb in OECD soil at the maximal concentrations recommended in agriculture. These responses were compared to lifecycle parameters such as survival, growth and reproduction.
Granulocyte morphometric alteration, lysosomal membrane stability, metallothionein concentration, and acetylcholinesterase activity were considered. In either copper sulphate or methiocarb exposure conditions the mean percentage variation of the pollutant-induced molecular and cellular biomarkers was consistent with the whole organism end-point responses. In particular pollutant-induced granulocyte enlargement, detected in either copper sulphate or methiocarb exposed organisms, showed to be a potential general biomarker that may be directly linked to organism health. Compared to the other biological responses to pollutants, it showed high sensitivity to pollutant exposure suggesting its possible applications as a sensitive, simple, and quick general biomarker for monitoring and assessment applications.
► A suite of biomarkers was standardized in the earthworm L. terrestris for detecting the pollutant induced stress syndrome. ► Exposure to either copper sulphate or methiocarb induced dramatic granulocyte enlargement. ► Pollutant induced granulocyte enlargement showed high sensitivity to pollutant exposure compared to other biomarkers. ► Granulocyte enlargement showed to be a potential general biomarker suitable to be included in a multi-biomarker strategy.</description><subject>Acetylcholinesterase - metabolism</subject><subject>Animal, plant and microbial ecology</subject><subject>Animals</subject><subject>Applied ecology</subject><subject>Assessments</subject><subject>Biological and medical sciences</subject><subject>Biomarker</subject><subject>Biomarkers - analysis</subject><subject>Cellular</subject><subject>Copper</subject><subject>Copper sulfate</subject><subject>Copper Sulfate - chemistry</subject><subject>Copper Sulfate - toxicity</subject><subject>Earthworm</subject><subject>Ecotoxicology, biological effects of pollution</subject><subject>Environmental Monitoring - methods</subject><subject>Exposure</subject><subject>Fundamental and applied biological sciences. Psychology</subject><subject>General aspects</subject><subject>Granulocytes - cytology</subject><subject>Granulocytes - drug effects</subject><subject>Hemolymph - drug effects</subject><subject>Lumbricus terrestris</subject><subject>Metallothionein - metabolism</subject><subject>Methiocarb</subject><subject>Methiocarb - chemistry</subject><subject>Methiocarb - toxicity</subject><subject>Monitoring</subject><subject>Oligochaeta - drug effects</subject><subject>Oligochaeta - growth & development</subject><subject>Oligochaeta - metabolism</subject><subject>Organisms</subject><subject>Pollutant</subject><subject>Pollutants</subject><subject>Reproduction - drug effects</subject><subject>Soil</subject><subject>Soil (material)</subject><subject>Soil Pollutants - chemistry</subject><subject>Soil Pollutants - toxicity</subject><subject>Techniques</subject><issn>0048-9697</issn><issn>1879-1026</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2011</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqFkM1u1DAURi0EotPCK4A3iG4SfJ04dpZtxU-lkbopYmk5zo3GQxIH2ynw9vVohrIDbyxZ5_r77iHkLbASGDQf9mW0LvmE80PJGUDJmpIJ9YxsQMm2AMab52TDWK2KtmnlGTmPcc_ykQpekjMOUlWcqw35du38ZMJ3DDRgXPwckbqZph1SNCHtfvow0e06dcHZNdKEIWMpuEjx1-Ij9jR5anc4OWtGuvhxXJOZU3xFXgxmjPj6dF-Qr58-3t98KbZ3n29vrraFrRuRChhYzU1ljTISQLSmt41RIq8i0OZnC73oQHR1bTiYqkKhTNcMCHJgUAOrLsj7479L8D_WXE1PLlocRzOjX6NWbQtCtFWVyct_kiAlq7hSAjIqj6gNPsaAg16Cy5Z-a2D64F_v9ZN_ffCvWaNz6Tz55hSydhP2T3N_hGfg3QkwMRsbgpmti3-5OsfXjGfu6shhlvfgMBwCcbbYu4A26d67_5Z5BFDXqXA</recordid><startdate>20110915</startdate><enddate>20110915</enddate><creator>Calisi, A.</creator><creator>Lionetto, M.G.</creator><creator>Schettino, T.</creator><general>Elsevier B.V</general><general>Elsevier</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7SU</scope><scope>8FD</scope><scope>C1K</scope><scope>FR3</scope><scope>KR7</scope><scope>7ST</scope><scope>7TV</scope><scope>SOI</scope></search><sort><creationdate>20110915</creationdate><title>Biomarker response in the earthworm Lumbricus terrestris exposed to chemical pollutants</title><author>Calisi, A. ; Lionetto, M.G. ; Schettino, T.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c465t-1f042a3ca8a71159adc6a850585ec3cac1d5b15b44a21a33e58ab6fe17f014103</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2011</creationdate><topic>Acetylcholinesterase - metabolism</topic><topic>Animal, plant and microbial ecology</topic><topic>Animals</topic><topic>Applied ecology</topic><topic>Assessments</topic><topic>Biological and medical sciences</topic><topic>Biomarker</topic><topic>Biomarkers - analysis</topic><topic>Cellular</topic><topic>Copper</topic><topic>Copper sulfate</topic><topic>Copper Sulfate - chemistry</topic><topic>Copper Sulfate - toxicity</topic><topic>Earthworm</topic><topic>Ecotoxicology, biological effects of pollution</topic><topic>Environmental Monitoring - methods</topic><topic>Exposure</topic><topic>Fundamental and applied biological sciences. Psychology</topic><topic>General aspects</topic><topic>Granulocytes - cytology</topic><topic>Granulocytes - drug effects</topic><topic>Hemolymph - drug effects</topic><topic>Lumbricus terrestris</topic><topic>Metallothionein - metabolism</topic><topic>Methiocarb</topic><topic>Methiocarb - chemistry</topic><topic>Methiocarb - toxicity</topic><topic>Monitoring</topic><topic>Oligochaeta - drug effects</topic><topic>Oligochaeta - growth & development</topic><topic>Oligochaeta - metabolism</topic><topic>Organisms</topic><topic>Pollutant</topic><topic>Pollutants</topic><topic>Reproduction - drug effects</topic><topic>Soil</topic><topic>Soil (material)</topic><topic>Soil Pollutants - chemistry</topic><topic>Soil Pollutants - toxicity</topic><topic>Techniques</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Calisi, A.</creatorcontrib><creatorcontrib>Lionetto, M.G.</creatorcontrib><creatorcontrib>Schettino, T.</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Environmental Engineering Abstracts</collection><collection>Technology Research Database</collection><collection>Environmental Sciences and Pollution Management</collection><collection>Engineering Research Database</collection><collection>Civil Engineering Abstracts</collection><collection>Environment Abstracts</collection><collection>Pollution Abstracts</collection><collection>Environment Abstracts</collection><jtitle>The Science of the total environment</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Calisi, A.</au><au>Lionetto, M.G.</au><au>Schettino, T.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Biomarker response in the earthworm Lumbricus terrestris exposed to chemical pollutants</atitle><jtitle>The Science of the total environment</jtitle><addtitle>Sci Total Environ</addtitle><date>2011-09-15</date><risdate>2011</risdate><volume>409</volume><issue>20</issue><spage>4456</spage><epage>4464</epage><pages>4456-4464</pages><issn>0048-9697</issn><eissn>1879-1026</eissn><coden>STENDL</coden><abstract>Earthworms are important organisms for the soil ecosystem. They are sensitive to toxic chemicals and represent useful bioindicator organisms for soil biomonitoring. Recently the use of biomarkers in earthworms has been increasingly investigated for soil monitoring and assessment purpose. The aim of the preset paper was to analyze the pollutant-induced response of a suite of cellular and biochemical biomarkers in the earthworm
Lumbricus terrestris exposed to copper sulphate or methiocarb in OECD soil at the maximal concentrations recommended in agriculture. These responses were compared to lifecycle parameters such as survival, growth and reproduction.
Granulocyte morphometric alteration, lysosomal membrane stability, metallothionein concentration, and acetylcholinesterase activity were considered. In either copper sulphate or methiocarb exposure conditions the mean percentage variation of the pollutant-induced molecular and cellular biomarkers was consistent with the whole organism end-point responses. In particular pollutant-induced granulocyte enlargement, detected in either copper sulphate or methiocarb exposed organisms, showed to be a potential general biomarker that may be directly linked to organism health. Compared to the other biological responses to pollutants, it showed high sensitivity to pollutant exposure suggesting its possible applications as a sensitive, simple, and quick general biomarker for monitoring and assessment applications.
► A suite of biomarkers was standardized in the earthworm L. terrestris for detecting the pollutant induced stress syndrome. ► Exposure to either copper sulphate or methiocarb induced dramatic granulocyte enlargement. ► Pollutant induced granulocyte enlargement showed high sensitivity to pollutant exposure compared to other biomarkers. ► Granulocyte enlargement showed to be a potential general biomarker suitable to be included in a multi-biomarker strategy.</abstract><cop>Kidlington</cop><pub>Elsevier B.V</pub><pmid>21783228</pmid><doi>10.1016/j.scitotenv.2011.06.058</doi><tpages>9</tpages></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0048-9697 |
| ispartof | The Science of the total environment, 2011-09, Vol.409 (20), p.4456-4464 |
| issn | 0048-9697 1879-1026 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_899155933 |
| source | MEDLINE; Access via ScienceDirect (Elsevier) |
| subjects | Acetylcholinesterase - metabolism Animal, plant and microbial ecology Animals Applied ecology Assessments Biological and medical sciences Biomarker Biomarkers - analysis Cellular Copper Copper sulfate Copper Sulfate - chemistry Copper Sulfate - toxicity Earthworm Ecotoxicology, biological effects of pollution Environmental Monitoring - methods Exposure Fundamental and applied biological sciences. Psychology General aspects Granulocytes - cytology Granulocytes - drug effects Hemolymph - drug effects Lumbricus terrestris Metallothionein - metabolism Methiocarb Methiocarb - chemistry Methiocarb - toxicity Monitoring Oligochaeta - drug effects Oligochaeta - growth & development Oligochaeta - metabolism Organisms Pollutant Pollutants Reproduction - drug effects Soil Soil (material) Soil Pollutants - chemistry Soil Pollutants - toxicity Techniques |
| title | Biomarker response in the earthworm Lumbricus terrestris exposed to chemical pollutants |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2024-12-28T18%3A20%3A51IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Biomarker%20response%20in%20the%20earthworm%20Lumbricus%20terrestris%20exposed%20to%20chemical%20pollutants&rft.jtitle=The%20Science%20of%20the%20total%20environment&rft.au=Calisi,%20A.&rft.date=2011-09-15&rft.volume=409&rft.issue=20&rft.spage=4456&rft.epage=4464&rft.pages=4456-4464&rft.issn=0048-9697&rft.eissn=1879-1026&rft.coden=STENDL&rft_id=info:doi/10.1016/j.scitotenv.2011.06.058&rft_dat=%3Cproquest_cross%3E1770328851%3C/proquest_cross%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=1770328851&rft_id=info:pmid/21783228&rft_els_id=S0048969711007145&rfr_iscdi=true |