Association and evolutionary studies of the melatonin receptor 1B gene (MTNR1B) in the self-contained population of Sorbs from Germany

Diabet. Med. 28, 1373–1380 (2011) Aims Several polymorphisms of the melatonin receptor 1B gene (MTNR1B) have been shown to be associated with elevated fasting plasma glucose and impaired early insulin release. The aim of this study was to assess the effects of MTNR1B variants on traits related to t...

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Veröffentlicht in:	Diabetic medicine 2011-11, Vol.28 (11), p.1373-1380
Hauptverfasser:	Dietrich, K., Birkmeier, S., Schleinitz, D., Breitfeld, J., Enigk, B., Müller, I., Böttcher, Y., Lindner, T., Stumvoll, M., Tönjes, A., Kovacs, P.
Format:	Artikel
Sprache:	eng
Schlagworte:	association study Biological and medical sciences Blood Glucose - metabolism Diabetes Mellitus, Type 2 - ethnology Diabetes Mellitus, Type 2 - genetics Diabetes Mellitus, Type 2 - metabolism Diabetes. Impaired glucose tolerance Endocrine pancreas. Apud cells (diseases) Endocrinopathies Ethnic Groups - genetics Etiopathogenesis. Screening. Investigations. Target tissue resistance Evolution, Molecular Feeding. Feeding behavior Female Fundamental and applied biological sciences. Psychology Germany - epidemiology Germany - ethnology glucose Glucose Tolerance Test Glycated Hemoglobin A - genetics Glycated Hemoglobin A - metabolism Humans Insulin Resistance - ethnology Insulin Resistance - genetics Linkage Disequilibrium Medical sciences Metabolic Syndrome - ethnology Metabolic Syndrome - genetics Metabolic Syndrome - metabolism Middle Aged Phylogeny polymorphism Polymorphism, Single Nucleotide Receptor, Melatonin, MT2 - genetics Receptor, Melatonin, MT2 - metabolism Type 2 diabetes Vertebrates: anatomy and physiology, studies on body, several organs or systems Vertebrates: endocrinology
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