B cell immunosenescence: different features of naive and memory B cells in elderly

Elderly people show a reduced protection against new infections and a decreased response to vaccines as a consequence of impairment of both cellular and humoral immunity. In this paper we have studied memory/naïve B cells in the elderly, evaluating surface immunoglobulin expression, production of th...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Biogerontology (Dordrecht) 2011-10, Vol.12 (5), p.473-483
Hauptverfasser:	Buffa, Silvio, Bulati, Matteo, Pellicanò, Mariavaleria, Dunn-Walters, Deborah K., Wu, Yu-Chang, Candore, Giuseppina, Vitello, Salvatore, Caruso, Calogero, Colonna-Romano, Giuseppina
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aged Aged, 80 and over Antigens B-Lymphocytes - cytology B-Lymphocytes - drug effects B-Lymphocytes - immunology Biomedical and Life Sciences Cell Biology Cells Cellular Senescence - immunology Cytokines Developmental Biology Geriatrics Geriatrics/Gerontology Germinal centers Humans Immune system Immunity (humoral) Immunoglobulins Immunoglobulins - immunology Immunologic Memory Immunological memory Immunology Immunosenescence Infection Inflammation Interleukin 10 Interleukin 4 Interleukin-10 - biosynthesis Ionomycin - pharmacology Laboratories Life Sciences Lymphocyte Activation Lymphocytes Lymphocytes B Memory cells Middle Aged Older people Research Paper somatic hypermutation Tetradecanoylphorbol Acetate - pharmacology Tumor necrosis factor- alpha Tumor necrosis factor-TNF Vaccines
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!