Selective N-Alkylation of Amines with Alcohols by Using Non-Metal-Based Acid-Base Cooperative Catalysis

Learning to cooperate: A straightforward method for the selective N‐mono‐ and dialkylation of amines with alcohols by means of non‐metal‐based catalysis promoted by TAPC is reported (see scheme). Selectivity of the N‐mono‐ and dialkylation, substrate scope and functional‐group tolerance are highligh...

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Veröffentlicht in:	Chemistry : a European journal 2011-10, Vol.17 (44), p.12262-12267
Hauptverfasser:	Du, Ya, Oishi, Shunsuke, Saito, Susumu
Format:	Artikel
Sprache:	eng
Schlagworte:	Alcohols Aliphatic compounds alkylation Amines Catalysis Chemistry cooperative catalysis hydrogen bonds Learning nucleophilic substitution Selectivity Substrates Tolerances
Online-Zugang:	Volltext
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