Filaggrin Mutations Associated with Skin and Allergic Diseases

Mutations in the filaggrin gene are associated with a broad range of skin and allergic diseases. The biology of this molecule and the role of mutations in its altered function offer new insights into a range of conditions not previously thought to be related to one another. Mutations in the filaggri...

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Veröffentlicht in:	The New England journal of medicine 2011-10, Vol.365 (14), p.1315-1327
Hauptverfasser:	Irvine, Alan D, McLean, W.H. Irwin, Leung, Donald Y.M
Format:	Artikel
Sprache:	eng
Schlagworte:	Allergic diseases Anti-Inflammatory Agents - therapeutic use Asthma Asthma - genetics Biological and medical sciences Cell cycle Cell division Dermatitis, Atopic - genetics Filaggrin Food Hypersensitivity - genetics General aspects Genomes Genomics Humans Hypersensitivity - genetics Intermediate Filament Proteins - deficiency Intermediate Filament Proteins - genetics Intermediate Filament Proteins - metabolism Medical sciences Mutation Proteins Skin diseases Skin Diseases - genetics
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