Complex genetic architecture of Drosophila aggressive behavior

Epistasis and pleiotropy feature prominently in the genetic architecture of quantitative traits but are difficult to assess in outbred populations. We performed a diallel cross among coisogenic Drosophila P-element mutations associated with hyperaggressive behavior and showed extensive epistatic and...

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Veröffentlicht in:	Proceedings of the National Academy of Sciences - PNAS 2011-10, Vol.108 (41), p.17070-17075
Hauptverfasser:	Zwarts, Liesbeth, Magwire, Michael M., Carbone, Mary Anna, Versteven, Marijke, Herteleer, Liesbet, Anholt, Robert R. H., Callaerts, Patrick, Mackay, Trudy F. C.
Format:	Artikel
Sprache:	eng
Schlagworte:	Abundance Aggression Aggression - physiology Aggressive behavior Animals Behavior, Animal - physiology Biological Sciences Brain Brain - anatomy & histology Crosses, Genetic diallel analysis Drosophila Drosophila melanogaster - anatomy & histology Drosophila melanogaster - genetics Drosophila melanogaster - physiology Epistasis Epistasis, Genetic Evolution Evolution, Molecular Evolutionary genetics Female Fitness Gene Expression Gene Regulatory Networks Genes Genes, Insect Genetic mutation Genetic variation Genotype & phenotype Genotypes Head heterozygosity Human aggression Human genetics Insects Male messenger RNA Mutation neural pathways P elements Phenotype pleiotropy Quantitative genetics quantitative traits Signal transduction Tissues Topology Transcription transcription (genetics) transposons
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