One-pot enzymatic production of 2-acetamido-2-deoxy- d-galactose (GalNAc) from 2-acetamido-2-deoxy- d-glucose (GlcNAc)

2-Acetamido-2-deoxy- d-galactose (GalNAc) is a common monosaccharide found in biologically functional sugar chains, but its availability is often limited due to the lack of abundant natural sources. In order to produce GalNAc from abundantly available sugars, 2-acetamido-2-deoxy- d-glucose (GlcNAc)...

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Veröffentlicht in:	Carbohydrate research 2011-11, Vol.346 (15), p.2432-2436
Hauptverfasser:	Inoue, Kousuke, Nishimoto, Mamoru, Kitaoka, Motomitsu
Format:	Artikel
Sprache:	eng
Schlagworte:	2-Acetamido-2-deoxy- d-galactose 2-Acetamido-2-deoxy- d-glucose Acetylgalactosamine - chemical synthesis Acetylgalactosamine - isolation & purification Acetylglucosamine - chemistry Acetylglucosamine - isolation & purification adenosine triphosphate Adenosine Triphosphate - chemistry Bacterial Proteins - chemistry Bifidobacterium Bifidobacterium - enzymology Biocatalysis cation exchange cation exchange chromatography Chromatography, Ion Exchange Enzyme Assays enzymes Galacto- N-biose/lacto- N-biose I pathway Kinetics N-Acetylhexosamine 1-kinase One-pot enzymatic reaction Phosphotransferases (Alcohol Group Acceptor) - chemistry sugars UDPglucose 4-Epimerase - chemistry UDPglucose-Hexose-1-Phosphate Uridylyltransferase - chemistry Uridine Diphosphate Glucose - chemistry Uridine Diphosphate N-Acetylglucosamine - chemistry
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