Neuron-glia interactions in glutamatergic neurotransmission: Roles of oxidative and glycolytic adenosine triphosphate as energy source

Glutamatergic neurotransmission accounts for a considerable part of energy consumption related to signaling in the brain. Chemical energy is provided by adenosine triphosphate (ATP) formed in glycolysis and tricarboxylic acid (TCA) cycle combined with oxidative phosphorylation. It is not clear wheth...

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Veröffentlicht in:	Journal of neuroscience research 2011-12, Vol.89 (12), p.1926-1934
Hauptverfasser:	Schousboe, A., Sickmann, H.M., Bak, L.K., Schousboe, I., Jajo, F.S., Faek, S.A.A., Waagepetersen, H.S.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adenosine Triphosphate - metabolism Animals Astrocytes ATP Brain Cell Communication - physiology Cell membranes Energy Metabolism - physiology Enzymes glia glutamate transport Glutamic Acid - metabolism Glutamic acid transporter Glyceraldehyde-3-phosphate dehydrogenase Glycolysis Humans Neuroglia - metabolism neuron Neurons Neurons - metabolism Neurotransmission Oxidative phosphorylation Phosphoglycerate kinase Postsynapse Signal transduction Sodium Synapses Synaptic Transmission - physiology Tricarboxylic acid cycle Vesicles Western blotting
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