Rat liver uncoupling protein 2: Changes induced by a fructose-rich diet

To evaluate the role of uncoupling protein 2 (UCP2) and peroxisome proliferator-activated receptors (PPARs) in the response of liver to glycoxidative stress triggered by administration of a fructose-rich diet (FRD). We assessed blood glucose in the fasting state and after a glucose load (glucose-oxi...

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Veröffentlicht in:	Life sciences (1973) 2011-10, Vol.89 (17-18), p.609-614
Hauptverfasser:	Castro, María C., Massa, María L., Del Zotto, Héctor, Gagliardino, Juan J., Francini, Flavio
Format:	Artikel
Sprache:	eng
Schlagworte:	alanine transaminase Animals aspartate transaminase blood glucose Blood Glucose - metabolism blood serum colorimetry Diet fasting fatty-acid synthase fructose Fructose - metabolism Fructose-rich diet gene expression Gene Expression Regulation genes glucose glucose oxidase glucose tolerance glycerol-3-phosphate acyltransferase Glycoxidative stress homeostasis insulin Insulin - blood Insulin Resistance Ion Channels - genetics Ion Channels - metabolism liver Liver - metabolism Liver uncoupling protein 2 Male messenger RNA Mitochondrial Proteins - genetics Mitochondrial Proteins - metabolism noninsulin-dependent diabetes mellitus obesity Peroxisome Proliferator-Activated Receptors - genetics Peroxisome Proliferator-Activated Receptors - metabolism Peroxisome proliferator-activated receptors regulation protein synthesis quantitative polymerase chain reaction radioimmunoassays Rats Rats, Wistar reactive oxygen species receptors triacylglycerols Triglycerides - blood Uncoupling Protein 2 Western blotting
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