Identification of Adipophilin as a Potential Plasma Biomarker for Colorectal Cancer Using Label-Free Quantitative Mass Spectrometry and Protein Microarray

The aim of this study was to identify a new plasma biomarker for use in early detection of colorectal cancer. Using the combination of hollow fiber membrane (HFM)-based low-molecular weight protein enrichment and two-dimensional image converted analysis of liquid chromatography and mass spectrometry...

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Veröffentlicht in:	Cancer epidemiology, biomarkers & prevention biomarkers & prevention, 2011-10, Vol.20 (10), p.2195-2203
Hauptverfasser:	MATSUBARA, Junichi, HONDA, Kazufumi, NAGAI, Hideo, LOKA, Tatsuya, OKUSAKA, Takuji, KOSUGE, Tomoo, TSUCHIDA, Akihiko, SHIMAHARA, Masashi, YASUNAMI, Yohichi, CHIBA, Tsutomu, YAMADA, Tesshi, ONO, Masaya, SEKINE, Shigeki, TANAKA, Yoshinori, KOBAYASHI, Michimoto, GIMAN JUNG, SAKUMA, Tomohiro, NAKAMORI, Shoji, SATA, Naohiro
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Area Under Curve Biological and medical sciences biomarkers Biomarkers, Tumor - blood Blood Proteins - metabolism Blotting, Western Case-Control Studies Chromatography, Liquid Colorectal cancer Colorectal Neoplasms - metabolism Electrophoresis, Gel, Two-Dimensional Female Fibers Follow-Up Studies Gastroenterology. Liver. Pancreas. Abdomen Humans Image processing Immunoenzyme Techniques Intestine Liquid chromatography Male Mass spectroscopy Medical sciences Membrane Proteins - metabolism Middle Aged Neoplasm Staging Perilipin-2 Plasma proteins Prognosis Prospective Studies Protein Array Analysis Protein arrays Proteome - analysis Stomach. Duodenum. Small intestine. Colon. Rectum. Anus Tandem Mass Spectrometry Tumors
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