Not a surgical vaccine: there is no case for boosting infant male circumcision to combat heterosexual transmission of HIV in Australia

To conduct a critical review of recent proposals that widespread circumcision of male infants be introduced in Australia as a means of combating heterosexually transmitted HIV infection. These arguments are evaluated in terms of their logic, coherence and fidelity to the principles of evidence‐based...

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Veröffentlicht in:Australian and New Zealand journal of public health 2011-10, Vol.35 (5), p.459-465
Hauptverfasser: Darby, Robert, Van Howe, Robert
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Van Howe, Robert
description To conduct a critical review of recent proposals that widespread circumcision of male infants be introduced in Australia as a means of combating heterosexually transmitted HIV infection. These arguments are evaluated in terms of their logic, coherence and fidelity to the principles of evidence‐based medicine; the extent to which they take account of the evidence for circumcision having a protective effect against HIV and the practicality of circumcision as an HIV control strategy; the extent of its applicability to the specifics of Australia's HIV epidemic; the benefits, harms and risks of circumcision; and the associated human rights, bioethical and legal issues. Our conclusion is that such proposals ignore doubts about the robustness of the evidence from the African random‐controlled trials as to the protective effect of circumcision and the practical value of circumcision as a means of HIV control; misrepresent the nature of Australia's HIV epidemic and exaggerate the relevance of the African random‐controlled trials findings to it; underestimate the risks and harm of circumcision; and ignore questions of medical ethics and human rights. The notion of circumcision as a ‘surgical vaccine’ is criticised as polemical and unscientific. Circumcision of infants or other minors has no place among HIV control measures in the Australian and New Zealand context; proposals such as these should be rejected.
doi_str_mv 10.1111/j.1753-6405.2011.00761.x
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subjects Acquired immune deficiency syndrome
AIDS
Australia
children
Circumcision
Circumcision, Male
Disease prevention
Disease transmission
Epidemics
Epidemiology
Evidence-Based Medicine
Hepatitis
Heterosexuality
HIV
HIV Infections - prevention & control
HIV Infections - transmission
Human immunodeficiency virus
Human rights
Humans
Immune system
Immunization
Infants
Infections
Legal issues
Lentivirus
Male
Males
Medical ethics
Proposals
Public health
random clinical trials
Randomized Controlled Trials as Topic
Retroviridae
Sexual health
Sexually transmitted diseases
Sexually Transmitted Diseases - prevention & control
Sexually Transmitted Diseases - transmission
STD
STIs
sub-Saharan Africa
Systematic review
Vaccines
title Not a surgical vaccine: there is no case for boosting infant male circumcision to combat heterosexual transmission of HIV in Australia
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