Pentoxifylline for treatment of sepsis and necrotizing enterocolitis in neonates

Mortality and morbidity due to neonatal sepsis and necrotizing enterocolitis (NEC) is high despite the use of potent antimicrobial agents. Agents that modulate inflammation may improve outcomes. Pentoxifylline, a phosphodiesterase inhibitor, is one such agent. The primary objectives were to assess t...

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Veröffentlicht in:	Cochrane database of systematic reviews 2011-10 (10), p.CD004205-CD004205
Hauptverfasser:	Haque, Khalid N, Pammi, Mohan
Format:	Artikel
Sprache:	eng
Schlagworte:	Anti-Bacterial Agents - therapeutic use Anti-Inflammatory Agents - therapeutic use Bacterial Infections - drug therapy Chemotherapy, Adjuvant Enterocolitis, Necrotizing - drug therapy Humans Infant, Newborn Infant, Premature Pentoxifylline - therapeutic use Phosphodiesterase Inhibitors - therapeutic use Randomized Controlled Trials as Topic Sepsis - drug therapy Sepsis - mortality
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