Complement and antibody primary immunodeficiency in juvenile systemic lupus erythematosus patients

Objective: To evaluate the frequency of primary immunodeficiencies (PID) in juvenile systemic lupus erythematosus (JSLE) patients. Methods: Some 72 JSLE patients were analyzed for levels of immunoglobulin classes and IgG subclasses and early components of the classical complement pathway. Determinat...

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Veröffentlicht in:	Lupus 2011-10, Vol.20 (12), p.1275-1284
Hauptverfasser:	Jesus, AA, Liphaus, BL, Silva, CA, Bando, SY, Andrade, LEC, Coutinho, A, Carneiro-Sampaio, M
Format:	Artikel
Sprache:	eng
Schlagworte:	Adolescent Antibodies Antibodies, Antinuclear - blood Autoantibodies - blood Autoimmune diseases Base Sequence Binding sites Child Child, Preschool Complement C1q - antagonists & inhibitors Complement C1q - deficiency Complement C1q - immunology Complement C2 - deficiency Complement C2 - genetics Complement C4 - deficiency Complement C4 - genetics Complement System Proteins - deficiency Complement System Proteins - genetics Disease DNA Primers - genetics Family medical history Female Gene Dosage Humans Immune system Immunoglobulins Immunoglobulins - blood Immunoglobulins - classification Immunologic Deficiency Syndromes - complications Immunologic Deficiency Syndromes - genetics Immunologic Deficiency Syndromes - immunology Infant Infections Lupus Lupus Erythematosus, Systemic - complications Lupus Erythematosus, Systemic - genetics Lupus Erythematosus, Systemic - immunology Male Medical records Mutation Pediatrics Sepsis
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