Effects of Icariin on Improving Erectile Function in Streptozotocin‐Induced Diabetic Rats

Icariin has been shown to improve penile hemodynamics in animal models of erectile dysfunction from cavernous nerve injury and castration. The effects of icariin on penile hemodynamics in diabetic animals remain to be determined. Transforming growth factor β1 (TGFβ1) has been implicated in the patho...

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Veröffentlicht in:	Journal of sexual medicine 2011-10, Vol.8 (10), p.2761-2772
Hauptverfasser:	Liu, Tao, Xin, Hua, Li, Wei‐Ren, Zhou, Feng, Li, Guang‐Yong, Gong, Yan‐Qing, Gao, Zhe‐Zhu, Qin, Xin‐Cheng, Cui, Wan‐Shou, Shindel, Alan W., Xin, Zhong‐Cheng
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Blotting, Western Cavernous Nerve Injury Corpus Cavernosum Diabetes Diabetes Mellitus, Experimental - complications Endothelium Erectile Dysfunction - drug therapy Erectile Dysfunction - etiology Erectile Function Flavonoids - therapeutic use Fluorescent Antibody Technique Male Muscle, Smooth, Vascular - chemistry Muscle, Smooth, Vascular - drug effects Nitric Oxide Synthase Nitric Oxide Synthase Type III - analysis Penile Erection - drug effects Penis - blood supply Penis - chemistry Penis - drug effects Rats Rats, Sprague-Dawley Signal Transduction - drug effects Smad Smad2 Protein - physiology Smooth Muscle Transforming Growth Factor beta1 - analysis Transforming Growth Factor-beta
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