Drug-Induced Yawning—A Review
Objective: To review the current literature on drug-induced yawning. Data Sources: Literature was accessed through MEDLINE/PubMed (1996-July 2011), International Pharmaceutical Abstracts (1997-July 2011), and EMBASE, using the search terms yawning, drug-induced yawning, and adverse drug reactions. S...
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| Veröffentlicht in: | The Annals of pharmacotherapy 2011-10, Vol.45 (10), p.1297-1301 |
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| container_title | The Annals of pharmacotherapy |
| container_volume | 45 |
| creator | Patatanian, Edna Williams, Nancy Toedter |
| description | Objective:
To review the current literature on drug-induced yawning.
Data Sources:
Literature was accessed through MEDLINE/PubMed (1996-July 2011), International Pharmaceutical Abstracts (1997-July 2011), and EMBASE, using the search terms yawning, drug-induced yawning, and adverse drug reactions.
Study Selection and Data Extraction:
Relevant clinical trials and case reports were selected and included to present background information. Bibliographies of all relevant articles were reviewed for additional citations.
Data Synthesis:
Yawning is a common stereotype behavior with unknown physiologic function that occurs in most vertebrates and humans as early as 15 weeks of intrauterine life. Yawning Is under the control of several neurotransmitters and neuropeptides, Including dopamine, serotonin, oxytocin, and acetylcholine. Among drugs, antidepressants, opioids, dopaminergic agents, benzodiazepines, and induction agents are the main pharmacologic classes associated with yawning.
Conclusions:
Yawning is rarely a serious adverse reaction and is not frequently listed in the drug summary. Most available data are based on case reports, small studies, and older literature. Clinicians should be aware of the agents commonly triggering this behavior. |
| doi_str_mv | 10.1345/aph.1Q255 |
| format | Article |
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To review the current literature on drug-induced yawning.
Data Sources:
Literature was accessed through MEDLINE/PubMed (1996-July 2011), International Pharmaceutical Abstracts (1997-July 2011), and EMBASE, using the search terms yawning, drug-induced yawning, and adverse drug reactions.
Study Selection and Data Extraction:
Relevant clinical trials and case reports were selected and included to present background information. Bibliographies of all relevant articles were reviewed for additional citations.
Data Synthesis:
Yawning is a common stereotype behavior with unknown physiologic function that occurs in most vertebrates and humans as early as 15 weeks of intrauterine life. Yawning Is under the control of several neurotransmitters and neuropeptides, Including dopamine, serotonin, oxytocin, and acetylcholine. Among drugs, antidepressants, opioids, dopaminergic agents, benzodiazepines, and induction agents are the main pharmacologic classes associated with yawning.
Conclusions:
Yawning is rarely a serious adverse reaction and is not frequently listed in the drug summary. Most available data are based on case reports, small studies, and older literature. Clinicians should be aware of the agents commonly triggering this behavior.</description><identifier>ISSN: 1060-0280</identifier><identifier>EISSN: 1542-6270</identifier><identifier>DOI: 10.1345/aph.1Q255</identifier><identifier>PMID: 21934035</identifier><identifier>CODEN: APHRER</identifier><language>eng</language><publisher>Los Angeles, CA: SAGE Publications</publisher><subject>Anesthetics, General - adverse effects ; Animals ; Apomorphine - adverse effects ; Arousal - drug effects ; Biological and medical sciences ; Dopamine Agonists - adverse effects ; Drug-Related Side Effects and Adverse Reactions ; Humans ; Medical sciences ; Pharmacology. Drug treatments ; Serotonin Uptake Inhibitors - adverse effects ; Yawning - drug effects</subject><ispartof>The Annals of pharmacotherapy, 2011-10, Vol.45 (10), p.1297-1301</ispartof><rights>2011 Harvey Whitney Books Company</rights><rights>2015 INIST-CNRS</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c275t-5528ecba1f5d21c79b8012728254cbd7814a6e945d7bd849ec19927f36b990353</citedby><cites>FETCH-LOGICAL-c275t-5528ecba1f5d21c79b8012728254cbd7814a6e945d7bd849ec19927f36b990353</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://journals.sagepub.com/doi/pdf/10.1345/aph.1Q255$$EPDF$$P50$$Gsage$$H</linktopdf><linktohtml>$$Uhttps://journals.sagepub.com/doi/10.1345/aph.1Q255$$EHTML$$P50$$Gsage$$H</linktohtml><link.rule.ids>314,780,784,21818,27923,27924,43620,43621</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=24754629$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/21934035$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Patatanian, Edna</creatorcontrib><creatorcontrib>Williams, Nancy Toedter</creatorcontrib><title>Drug-Induced Yawning—A Review</title><title>The Annals of pharmacotherapy</title><addtitle>Ann Pharmacother</addtitle><description>Objective:
To review the current literature on drug-induced yawning.
Data Sources:
Literature was accessed through MEDLINE/PubMed (1996-July 2011), International Pharmaceutical Abstracts (1997-July 2011), and EMBASE, using the search terms yawning, drug-induced yawning, and adverse drug reactions.
Study Selection and Data Extraction:
Relevant clinical trials and case reports were selected and included to present background information. Bibliographies of all relevant articles were reviewed for additional citations.
Data Synthesis:
Yawning is a common stereotype behavior with unknown physiologic function that occurs in most vertebrates and humans as early as 15 weeks of intrauterine life. Yawning Is under the control of several neurotransmitters and neuropeptides, Including dopamine, serotonin, oxytocin, and acetylcholine. Among drugs, antidepressants, opioids, dopaminergic agents, benzodiazepines, and induction agents are the main pharmacologic classes associated with yawning.
Conclusions:
Yawning is rarely a serious adverse reaction and is not frequently listed in the drug summary. Most available data are based on case reports, small studies, and older literature. Clinicians should be aware of the agents commonly triggering this behavior.</description><subject>Anesthetics, General - adverse effects</subject><subject>Animals</subject><subject>Apomorphine - adverse effects</subject><subject>Arousal - drug effects</subject><subject>Biological and medical sciences</subject><subject>Dopamine Agonists - adverse effects</subject><subject>Drug-Related Side Effects and Adverse Reactions</subject><subject>Humans</subject><subject>Medical sciences</subject><subject>Pharmacology. Drug treatments</subject><subject>Serotonin Uptake Inhibitors - adverse effects</subject><subject>Yawning - drug effects</subject><issn>1060-0280</issn><issn>1542-6270</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2011</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNpt0LtOwzAUBmALgWgpDLwAdAHEkOJrbI9VuVWqhEAwMFmO7ZRUaVLshoqNh-AJeRIMDbAwnTN8OpcfgH0EB4hQdqYXTwN0ixnbAF3EKE5SzOFm7GEKE4gF7ICdEGYQQomw3AYdjCShkLAuODz3zTQZV7YxzvYf9aoqqunH2_uwf-deCrfaBVu5LoPba2sPPFxe3I-uk8nN1Xg0nCQGc7ZMGMPCmUyjnFmMDJeZgAhzLDCjJrNcIKpTJymzPLOCSmeQlJjnJM2kjIeQHjhZz134-rlxYanmRTCuLHXl6iYoIVMiCWE8ytO1NL4OwbtcLXwx1_5VIai-4lAxDvUdR7QH7dQmmzv7K3_-j-CoBToYXeZeV6YIf45yRlMsozteu6CnTs3qxlcxjX82fgKS43H3</recordid><startdate>20111001</startdate><enddate>20111001</enddate><creator>Patatanian, Edna</creator><creator>Williams, Nancy Toedter</creator><general>SAGE Publications</general><general>Whitney</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>20111001</creationdate><title>Drug-Induced Yawning—A Review</title><author>Patatanian, Edna ; Williams, Nancy Toedter</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c275t-5528ecba1f5d21c79b8012728254cbd7814a6e945d7bd849ec19927f36b990353</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2011</creationdate><topic>Anesthetics, General - adverse effects</topic><topic>Animals</topic><topic>Apomorphine - adverse effects</topic><topic>Arousal - drug effects</topic><topic>Biological and medical sciences</topic><topic>Dopamine Agonists - adverse effects</topic><topic>Drug-Related Side Effects and Adverse Reactions</topic><topic>Humans</topic><topic>Medical sciences</topic><topic>Pharmacology. Drug treatments</topic><topic>Serotonin Uptake Inhibitors - adverse effects</topic><topic>Yawning - drug effects</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Patatanian, Edna</creatorcontrib><creatorcontrib>Williams, Nancy Toedter</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>The Annals of pharmacotherapy</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Patatanian, Edna</au><au>Williams, Nancy Toedter</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Drug-Induced Yawning—A Review</atitle><jtitle>The Annals of pharmacotherapy</jtitle><addtitle>Ann Pharmacother</addtitle><date>2011-10-01</date><risdate>2011</risdate><volume>45</volume><issue>10</issue><spage>1297</spage><epage>1301</epage><pages>1297-1301</pages><issn>1060-0280</issn><eissn>1542-6270</eissn><coden>APHRER</coden><abstract>Objective:
To review the current literature on drug-induced yawning.
Data Sources:
Literature was accessed through MEDLINE/PubMed (1996-July 2011), International Pharmaceutical Abstracts (1997-July 2011), and EMBASE, using the search terms yawning, drug-induced yawning, and adverse drug reactions.
Study Selection and Data Extraction:
Relevant clinical trials and case reports were selected and included to present background information. Bibliographies of all relevant articles were reviewed for additional citations.
Data Synthesis:
Yawning is a common stereotype behavior with unknown physiologic function that occurs in most vertebrates and humans as early as 15 weeks of intrauterine life. Yawning Is under the control of several neurotransmitters and neuropeptides, Including dopamine, serotonin, oxytocin, and acetylcholine. Among drugs, antidepressants, opioids, dopaminergic agents, benzodiazepines, and induction agents are the main pharmacologic classes associated with yawning.
Conclusions:
Yawning is rarely a serious adverse reaction and is not frequently listed in the drug summary. Most available data are based on case reports, small studies, and older literature. Clinicians should be aware of the agents commonly triggering this behavior.</abstract><cop>Los Angeles, CA</cop><pub>SAGE Publications</pub><pmid>21934035</pmid><doi>10.1345/aph.1Q255</doi><tpages>5</tpages></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 1060-0280 |
| ispartof | The Annals of pharmacotherapy, 2011-10, Vol.45 (10), p.1297-1301 |
| issn | 1060-0280 1542-6270 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_896393357 |
| source | MEDLINE; SAGE Complete A-Z List |
| subjects | Anesthetics, General - adverse effects Animals Apomorphine - adverse effects Arousal - drug effects Biological and medical sciences Dopamine Agonists - adverse effects Drug-Related Side Effects and Adverse Reactions Humans Medical sciences Pharmacology. Drug treatments Serotonin Uptake Inhibitors - adverse effects Yawning - drug effects |
| title | Drug-Induced Yawning—A Review |
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